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"Alcohol"

Case Report

Central Pontine Myelinolysis Induced by Alcohol Withdrawal: A Case Report
Jae Ho Kim, Sae Hyun Kim, Ho Joong Jeong, Young Joo Sim, Dong Kyu Kim, Ghi Chan Kim
Ann Rehabil Med 2017;41(1):148-152.   Published online February 28, 2017
DOI: https://doi.org/10.5535/arm.2017.41.1.148

Central pontine myelinolysis (CPM) is a demyelinating disorder characterized by the loss of myelin in the center of the basis pons, and is mainly caused by the rapid correction of hyponatremia. We report the case of a young woman who presented with gait disturbance and alcohol withdrawal, and who was eventually diagnosed with CPM. Generally, the cause and pathogenesis of CPM in chronic alcoholics remain unclear. In this cases, the CPM may be unrelated to hyponatremia or its correction. However, it is possible that the osmotic pressure changes due to refeeding syndrome after alcohol withdrawal was the likely cause in this case. This case illustrates the need for avoiding hasty, and possibly incomplete diagnoses, and performing more intensive test procedures to ensure a correct diagnosis.

Citations

Citations to this article as recorded by  
  • Central Pontine Myelinolysis: A Rare Case Secondary to Chronic Alcoholism
    Ishwar Hasabi, M. Yashwanth, B. E. Kalinga, Vishwanath Patil, N. K. Seetaram
    APIK Journal of Internal Medicine.2025;[Epub]     CrossRef
  • Case Report: Quantitative Evaluation of Gait Function Following Treatment Progression in a Patient with Central Pontine Myelinolysis
    Sangho Ji, Sunny Kang, Jiwoo Kim, Youngjo So, Sangkwan Lee, Cheol-Hyun Kim
    The Journal of Internal Korean Medicine.2024; 45(2): 190.     CrossRef
  • Central Pontine Myelinolysis Induced by Rapid Correction of Hyponatremia in a Patient With Chronic Alcohol Use Disorder: A Case Report
    Amjad M Mohamadiyeh, Sajad J Allami, Liza Thomas, Uzma Sabahat
    Cureus.2024;[Epub]     CrossRef
  • Rapid Correction of Hyponatremia With Isotonic Saline Leading to Central Pontine Myelinolysis
    Sulhera Khan, Sonia Das, Wajeeha Batool, Bareerah S Khan, Marium Khan
    Cureus.2023;[Epub]     CrossRef
  • OSMOTIC DEMYELINATION SYNDROME IN UNUSUAL SETTINGS
    Sakthi Velayutham S, Sowmini PR, Malcolm Jeyaraj K, Sathish Kumar M, Arunan S
    PARIPEX INDIAN JOURNAL OF RESEARCH.2022; : 36.     CrossRef
  • Diagnostic des anomalies neurologiques liées à l’hépatopathie alcoolique
    K. Nelson, D. Landry
    EMC - Hépatologie.2022; 37(1): 1.     CrossRef
  • Das Auftreten der zentralen pontinen Myelinolyse während des qualifizierten Entzugs von Alkohol. Ein Fallbericht
    Phileas J. Proskynitopoulos, Gregor Szycik, Stefan Bleich, Eva Janke, Alexander Glahn
    neuropsychiatrie.2020; 34(4): 175.     CrossRef
  • 7,277 View
  • 87 Download
  • 1 Web of Science
  • 7 Crossref

Original Article

Ultrasound-Guided 50% Ethyl Alcohol Injection for Patients With Malleolar and Olecranon Bursitis: A Prospective Pilot Study
Ji Seong Hong, Hyoung Seop Kim, Jin Hyung Lee
Ann Rehabil Med 2016;40(2):310-317.   Published online April 25, 2016
DOI: https://doi.org/10.5535/arm.2016.40.2.310
Objective

To evaluate the feasibility and effect of ultrasound-guided ethyl alcohol injection on malleolar and olecranon synovial proliferative bursitis.

Methods

Twenty-four patients received ultrasound-guided 50% diluted ethyl alcohol injection at the site of synovial proliferative bursitis after aspiration of the free fluid.

Results

Swelling and symptoms significantly decreased in 13 of the 24 patients without any complications. Eleven patients had partial improvement in swelling and symptoms.

Conclusion

Ultrasound-guided alcohol injection could be an alternative therapeutic option before surgery in patients with chronic intractable malleolar and olecranon synovial proliferative bursitis.

Citations

Citations to this article as recorded by  
  • Bursitis in the nonarticular part of the mandible in atopic dermatitis
    Natsumi Miyata, Toshihiko Hayashi, Joji Hayashi, Takuya Nishio, Sayaka Yuzawa, Naoko Aoki, Takeshi Yamao
    Oral and Maxillofacial Surgery.2025;[Epub]     CrossRef
  • Intrabursal Doxycycline Sclerotherapy for Recurrent Olecranon Bursitis of the Elbow: A Case Control Study
    Daniel McDermott, Dorothy Wakefield, Marc Kowalsky, Paul Sethi, Mark A. Vitale, Bernard F. Morrey
    Journal of Hand Surgery Global Online.2024; 6(4): 504.     CrossRef
  • Sodium Tetradecyl Sulphate Sclerotherapy for Lateral Malleolar Bursitis of the Ankle
    Yeo Kwon Yoon, Jae Han Park, Jiyoun Kim, Seung Hwan Han, Seung Hwan Shin, Jin Woo Lee, Kwang Hwan Park
    Clinics in Orthopedic Surgery.2022; 14(2): 289.     CrossRef
  • Saline Load Test and Quilting Sutures to Treat Intractable Lateral Malleolar Bursitis
    Ho Won Lee, Ik Yang, Yuxuan Liu, Jong-Hwa Lee, Hyong Nyun Kim
    The Journal of Foot and Ankle Surgery.2021; 60(2): 345.     CrossRef
  • Clinical Management of Olecranon Bursitis: A Review
    Nzuekoh N. Nchinda, Jennifer Moriatis Wolf
    The Journal of Hand Surgery.2021; 46(6): 501.     CrossRef
  • Outcome of triamcinolone acetonide injection for lateral malleolar bursitis
    Tae Sik Goh, Tae Young Ahn, Kyeongbaek Kim, Won Chul Shin, Nam Hoon Moon, Seung Hun Woo
    Journal of Orthopaedic Surgery.2020;[Epub]     CrossRef
  • Medial Malleolar Bursitis in an Elite Competitive Alpine Skier: A Case Report
    Stefan Fröhlich, Stefan M. Zimmermann, Reto Sutter, Walter O. Frey, Jörg Spörri
    Current Sports Medicine Reports.2020; 19(10): 399.     CrossRef
  • 8,807 View
  • 93 Download
  • 6 Web of Science
  • 7 Crossref

Case Reports

Treatment of Chronic Isolated Finger Flexor Tenosynovitis Through 50% Dehydrated Alcohol Installation
Jae Eun Shin, Jung Hyun Park, Ho Sung Yi, Byung Kook Ye, Hyoung Seop Kim
Ann Rehabil Med 2013;37(4):586-590.   Published online August 26, 2013
DOI: https://doi.org/10.5535/arm.2013.37.4.586

The isolated idiopathic finger flexor tenosynovitis is a rare condition, related to diversed etiologies. The traditional treatment of flexor tenosynovitis includes medications and injection of steroids. If the conservative treatment is not effective, surgical management is usually recommended. And alcohol installations have been rarely performed. We are reporting an extremely rare case of a 56-year-old man who had chronic idiopathic isolated finger flexor tenosynovitis which was treated through alcohol injections. The patient had not yet been treated despite of medication and serial injections of steroid. We performed 1 mL of 50% ethanol injection for the initial treatment and the second injection was done in the same way 10 months later due to the improvements of the patient's clinical symptoms and images of the follow-up ultrasonography. As a result, the authors suggest alcohol installation as an alternative non-surgical treatment for flexor tenosynovitis when other conservative managements are not effective enough.

Citations

Citations to this article as recorded by  
  • Ultrasound-Guided 50% Ethyl Alcohol Injection for Patients With Malleolar and Olecranon Bursitis: A Prospective Pilot Study
    Ji Seong Hong, Hyoung Seop Kim, Jin Hyung Lee
    Annals of Rehabilitation Medicine.2016; 40(2): 310.     CrossRef
  • 4,981 View
  • 231 Download
  • 1 Crossref
Sonographically Guided Alcohol Injection in Painful Stump Neuroma
Kil-Byung Lim, Young-Sup Kim, Jeong-A Kim
Ann Rehabil Med 2012;36(3):404-408.   Published online June 30, 2012
DOI: https://doi.org/10.5535/arm.2012.36.3.404

Stump neuroma is a common cause of pain from disorganized proliferation of nerve fascicles occurring after limb amputation. Ultrasound guided alcohol injection in painful stump neuroma has been tried as a new treatment approach. Herein, we report 2 male patients, who had traumatic amputation and claimed severe and diffuse burning pain in the stump area. Neuroma at the distal end of an amputated nerve was clearly identified on sonography. The patients gradually developed increasing severe pain that could not be managed with conservative care. They were treated with neurolysis using alcohol solution. Using ultrasonographical guidance, 1.2 ml of 100% dehydrated alcohol was injected into the nerves proximal to neuroma. No complications occurred. The patients were initially pain free. After a few months, however, their stump pain recurred slightly. Repeat neurolysis was performed using 0.3 ml of 100% dehydrated alcohol. During the three months follow-up period, mild stump pain occurred but the patients did not require any analgesics.

Citations

Citations to this article as recorded by  
  • Neuropathic postamputation residual limb pain after combat trauma: an evidence-based review of diagnosis and injection therapy
    B.V. Zadorozhna, A.I. Bohdan
    INTERNATIONAL NEUROLOGICAL JOURNAL.2025; 20(8): 467.     CrossRef
  • A Review of Nonsurgical Neurolytic Procedures for Neuropathic Pain
    Mayank Gupta, Rany Abdallah, Alaa Abd-Elsayed, Krishnan Chakravarthy, Miles Day, Timothy Deer, Sudhir Diwan, Nebojsa Knezevic, Neel Mehta, Michael Schatman, Amol Soin, Peter Staats
    Journal of Pain Research.2025; Volume 18: 879.     CrossRef
  • Ultrasound-guided platelet-rich plasma injection for traumatic painful neuroma of brachial plexus: a case report and literature review
    Haifeng Zhu, Zixuan Deng, Yongqi Xie, Guifeng Qian, Danyu Wang, Shaodong Xie, Yunyi Zhang, Peichun Yan
    Frontiers in Neurology.2025;[Epub]     CrossRef
  • Ethanol and NaCl-Induced Gold Nanoparticle Aggregation Toxicity toward DNA Investigated with a DNA/GCE Biosensor
    Jana Blaškovičová, Vlastimil Vyskočil, Michal Augustín, Andrea Purdešová
    Sensors.2023; 23(7): 3425.     CrossRef
  • Management interventions for amputation stump neuromas: evidence based review and cost-benefit analysis
    Ernest A. Azzopardi, Philippa Stewart, Dean Edward Boyce, Maxwell Murison, Hazim Sadideen, Matteo Tretti Clementoni
    Laser Therapy.2023;[Epub]     CrossRef
  • Prevalence of residual limb pain and symptomatic neuromas after lower extremity amputation: a systematic review and meta-analysis
    Emile B. List, David D. Krijgh, Enrico Martin, J. Henk Coert
    Pain.2021; 162(7): 1906.     CrossRef
  • Diagnostic Criteria for Symptomatic Neuroma
    Denise M. J. Arnold, Suzanne C. Wilkens, J. Henk Coert, Neal C. Chen, Ivica Ducic, Kyle R. Eberlin
    Annals of Plastic Surgery.2019; 82(4): 420.     CrossRef
  • Peripheral Interventions for Painful Stump Neuromas of the Lower Limb
    Stephanie A. Poyntz, Nicholas M. Hacking, Milind Dalal, Stephen Fowler
    The Clinical Journal of Pain.2018; 34(3): 285.     CrossRef
  • The role of sonographically guided alcohol instillation in treating painful neuroma: Sonographically guided alcohol instillation
    Vesna Antonijević, Tatjana Brkić, Ivana Marković, Nikola Lađević, Anđela Magdelinić, Jelena Jovičić
    Serbian Journal of Anesthesia and Intensive Therapy.2018; 40(3-4): 95.     CrossRef
  • Multiple Neuromas Cause Painful “Jumping Stump” in a Transfemoral Amputee
    Montana Buntragulpoontawee, Nuttaya Pattamapaspong, Siam Tongprasert
    The International Journal of Lower Extremity Wounds.2016; 15(3): 271.     CrossRef
  • Imaging Features Associated With Posttraumatic Breast Neuromas
    Shaza AlSharif, Romuald Ferré, Atilla Omeroglu, Mona El Khoury, Benoît Mesurolle
    American Journal of Roentgenology.2016; 206(3): 660.     CrossRef
  • Ultrasound-Guided Steroid Injection to the Residual Limb Stalk Facilitated the Treatment of a Painful Above-Knee Residual Limb Neuroma
    Montana Buntragulpoontawee, Chen-Yu Hung, Jeeranan Rapipong, Ke-Vin Chang
    MYOPAIN.2015; 23(1-2): 52.     CrossRef
  • Treatment of the Traumatic Neuroma
    Youn-Tae Roh, Il-Jung Park
    Journal of the Korean Society for Surgery of the Hand.2014; 19(4): 209.     CrossRef
  • Management of Neuromas of the Upper Extremity
    David M. Brogan, Sanjeev Kakar
    Hand Clinics.2013; 29(3): 409.     CrossRef
  • Musculoskeletal Ultrasound in Physical Medicine and Rehabilitation
    George W. Deimel, Elena J. Jelsing, Mederic M. Hall
    Current Physical Medicine and Rehabilitation Reports.2013; 1(1): 38.     CrossRef
  • 6,136 View
  • 55 Download
  • 15 Crossref

Original Article

Alcohol Use in Community-dwelling Persons with Spinal Cord Injury.
Jung, Sung Jin , Leigh, Ja Ho , Shin, Hyung Ik
J Korean Acad Rehabil Med 2010;34(4):424-431.
Objective
To investigate the patterns of alcohol use among community-dwelling persons with spinal cord injury (SCI) and compare the results with those from general populations. Method: The persons with SCI living in community were recruited. They answered the self-administered questionnaire which was made based on the questionnaire of the third Korea National Health and Nutrition Examination Survey for data comparisons. The questionnaire consisted of the questions about personal information, drinking duration, drinking frequency, drinking amount, and impaired control over drinking. Results: Questionnaires of 340 persons with SCI from twenties to fifties were analysed. The annual and monthly drinking rates of SCI subjects were lower than those of general populations. In male, drinking frequency of SCI subjects was lower than that of general populations. In both male and female, risky drinking rates were lower than those of general populations. The degree of impaired control over drinking of SCI subjects was higher than that of general populations. Conclusion: Fewer persons with SCI used alcohol than general populations. But, the degree of alcohol dependence of SCI persons was higher than that of general populations. (J Korean Acad Rehab Med 2010; 34: 424-431)
  • 1,374 View
  • 11 Download

Case Report

Treatment of Synovial Proliferative Subdeltoid Bursitis through Alcohol Installation: A case report.
Shin, Jung Bin , Joo, Seung Ho , Kim, Hyoung Seop , Cho, Hyung Keun
J Korean Acad Rehabil Med 2010;34(1):106-109.
For patients with bursitis, the treatment modality of choice was conservative treatment, and those who did not experience symptom relief usually received surgery. However, we have been able to treat a patient with chronic proliferative subdeltoid bursitis through alcohol instillation. The patient complained of aggravating right shoulder area pain particularly on abduction or flexion of his arm. Ultrasonographic examination revealed that there was notable synovial thickening, fluid collection and proliferative pannus in the subdeltoid bursa. Steroid was injected for treatment but after 9 days, synovial proliferation and synovial fluid collection remained unchanged. After additional 7 days, 70% isopropyl alcohol 5 ml was injected into the subdeltoid bursa via ultrasonograph-guided injection, followed by normal saline 10 ml injection to dilute the previously injected alcohol in order to re-aspirate. On the following check-up 3 weeks after, decrease in synovial proliferation along with normal ultrasonographic results other than slightly thickened bursa wall was noted. (J Korean Acad Rehab Med 2010; 34: 106-109)
  • 1,519 View
  • 26 Download

Original Articles

Autonomic Function in Chronic Alcoholic Patients.
Jung, Tae Ho , Park, Dong Sik , Nam, Hee Seung , Jung, Hyun Oh , Lee, Sang Eok , Kim, Dong Hyun
J Korean Acad Rehabil Med 2009;33(3):321-326.
Objective
To investigate the relationship among the alcohol drinking history, autonomic symptom scores (ASS), and the autonomic functions measured with sympathetic skin response (SSR) and heart rate variability (HRV) of alcoholic patients, and to assess the difference between the values from the autonomic function tests of patients and normal controls. Method: SSR and HRV were measured in 44 patients and 26 controls. ASS and Toronto clinical neuropathy scoring system (TCNSS) scores were also assessed. For the HRV, the mean heart rate, standard deviation of the NN intervals (SDNN), total power (TP), very low frequency (VLF), low frequency (LF), and high frequency (HF) in both the supine and standing positions were evaluated. For the SSR, the onset latency and amplitude of both the palm and sole were measured. Results: There were no significant relationships among the alcohol history, the TCNSS, and the results of the autonomic function tests. There were, however, significant relationships among their ASS and some values from autonomic function tests [i.e., the sole amplitudes, the SDNNs (supine), and the TPs (standing)]. There were significant differences between the sole amplitudes of the patients and controls. In HRV, there were significant differences between the patients and controls with respect to their SDNNs and TPs at a standing position. Conclusion: Autonomic function tests such as SSR and HRV are related to ASS, but not to alcohol history and TCNSS. Moreover, the values from the autonomic function tests of the alcoholic patients decreased, unlike the normal controls. (J Korean Acad Rehab Med 2009; 33: 321-326)
  • 1,530 View
  • 12 Download
The Effect of Motor Point Block with Alcohol on Hip Adductor Muscles in Spastic Cerebral Palsy.
Ryu, Soo Jin , Kim, Dong Hyuk , Kim, Eun Jin , Cho, Yun Kyung , Lee, Sung Hoon , Kang, Eun Young
J Korean Acad Rehabil Med 2007;31(4):472-477.
Objective
To investigate the effectiveness of motor point blocking using 70% alcohol for the treatment of spasticity in patients with cerebral palsy. Method: 16 patients with spastic cerebral palsy were injected at both hip adductor muscles with 70% alcohol. The severity of spasticity was assessed with the modified Ashworth scale (MAS) of adductor muscles, and the passive range of motion (PROM) of hip abduction. MAS and PROM were measured before, immediately after, and 1 and 3 months after the motor point block. Satisfaction of caregivers was also checked 3 months after the procedure. Results: The MAS prior to the motor point block and at 3 months after the procedure were 4.44±0.62 and 3.63±1.16. The PROM before motor point block and at 3 months after the procedure were 21.81±14.14° and 32.81±12.37°. 11 out of 16 (68.8%) caregivers reported high satisfaction. Conclusion: Motor point block with 70% alcohol to the hip adductor muscles could be a safe and cost-effective procedure for relieving the localized spasticity of hip adductor muscles in spastic cerebral palsy. (J Korean Acad Rehab Med 2007; 31: 472-477)
  • 1,887 View
  • 38 Download
The Changes after Alcohol Neurolysis of the Tibial Nerve Motor Branches to Gastrocnemius Muscles in Poststroke Patients.
Park, Gi Young , Ro, Hye Jung , Kim, Jong Min
J Korean Acad Rehabil Med 2003;27(4):545-550.
OBJECTIVE
To evaluate the effectiveness and electrophysiological changes after alcohol neurolysis of the tibial nerve motor branches to gastrocnemius muscles on the treatment of ankle spasticity in stroke patients. METHOD: Fourteen poststroke hemiplegic patients who had an abnormal gait pattern due to the ankle spasticity participated. They were evaluated by modified Ashworth scale (MAS) score, passive range of motion (PROM) of ankle, and ankle clonus, and were studied using electrophysiological measurements such as amplitude and latency of H-reflex and M response, and H/M ratio. 50% alcohol was injected into the tibial nerve motor branches to the both gastrocnemius muscles with electromyography guidance. Follow-up evaluations were performed immediately, and then, at the one-week, one-month, and three-months following the neurolysis. RESULTS: The MAS scores significantly decreased and the PROM of the ankle significantly increased. The M response and H-reflex amplitude of gastrocnemius muscles significantly decreased after the neurolysis and they had a tendency to increase at the 3-months follow-up. Also, H/M ratio significantly decreased. There were no serious postinjection complications. CONCLUSION: Alcohol neurolysis of the tibial nerve motor branches was an effective and safe method for the treatment of the ankle spasticity in poststroke hemiplegic patients.
  • 1,464 View
  • 0 Download
Case Report
Acute Rhabdomyolysis and Ischemia of the Spinal Cord Following the Heavy Alcohol Ingestion: A case report.
Cho, Kang Hee , Kang, San Kyong , Kang, Sang Kuk , Kwon, Soon Tae
J Korean Acad Rehabil Med 2002;26(5):631-634.

Ischemic myelopathy is a rare and uncommon disease than the cerebral ischemia. Ischemia of spinal cord usually occur in the midthoracic regions (T4-T8). The major arteries supplying spinal cord are anterior and posterior spinal arteries. Anterior spinal artery is more responsible for the ischemic change of the spinal cord. We report a 45 years old man with ischemia of the spinal cord and acute renal failure due to rhabdomyolysis following the heavy alcohol ingestion. (J Korean Acad Rehab Med 2002; 26: 631-634)

  • 1,387 View
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