Byung Chan Lee, Beom Suk Kim, Byeong-Ju Lee, Chang-Won Moon, Chul-Hyun Park, Dong Hwan Kim, Dong Hwan Yun, Donghwi Park, Doo Young Kim, Du Hwan Kim, Gi-Wook Kim, Hyun Jung Kim, Il-Young Jung, In Jong Kim, Jae Hyeon Park, Jae-Hyun Lee, Jaeki Ahn, Jae-Young Lim, Jin A Yoon, Jong Hwa Lee, Jong-Moon Hwang, Keewon Kim, Kyeong Eun Uhm, Kyoung Hyo Choi, Kyung Eun Nam, Kyunghoon Min, Min Cheol Chang, Myung Woo Park, Nackhwan Kim, Hyeng-Kyu Park, Seong Hun Kim, Seoyon Yang, Sun Jae Won, Sung Gyu Moon, Sung Joon Chung, Sungju Jee, Woo Hyung Lee, Yong Bok Park, Yoonju Na, Yu Hui Won, Yu Jin Im, Yu Sung Yoon, Yun Jung Lee, Yunsoo Soh, Jae-Young Han
Ann Rehabil Med 2025;49(3):113-138. Published online June 30, 2025
Objective Primary frozen shoulder causes significant pain and progressively restricts shoulder movements. Diagnosis is primarily clinically based on patient history and physical examination. Management is mainly non-invasive owing to its self-limiting clinical course. However, clinical practice guidelines for frozen shoulder have not yet been developed in Korea. The developed guidelines aim to provide evidence-based recommendations for the diagnosis and treatment of frozen shoulder.
Methods A guideline development committee reviewed the literature from four databases (PubMed, Embase, Cochrane Library, and KMbase). Using the PICO (Population, Intervention, Comparator, and Outcome) framework, the committee formulated two backgrounds and 16 key questions to address common clinical concerns. Recommendations were made using the Grading of Recommendations, Assessment, Development, and Evaluation framework.
Results Diabetes, thyroid disease, and dyslipidemia significantly increase the risk of developing a frozen shoulder. Although frozen shoulder is often self-limiting, some patients may experience long-term disabilities. Ultrasound and magnetic resonance imaging should be used as adjunctive tools alongside clinical diagnosis, and not as independent diagnostic methods. Noninvasive approaches, such as medications, physical modalities, exercises, electrical stimulation, and manual therapy, may reduce pain and improve shoulder function. Other noninvasive interventions have limited evidence, and their application should be based on clinical judgment. Intra-articular steroid injections are recommended for treatment, and physiotherapy or hydrodilatation with steroid injections can also be beneficial.
Conclusion These guidelines provide evidence-based recommendations for diagnosing and treating primary frozen shoulder.
Citations
Citations to this article as recorded by
Comparison of efficacy of intra-articular injection of platelet-rich plasma with bupivacaine and steroid combination in chronic shoulder pain Naveen Malhotra, Neha Sinha, Amit Kumar, Ritu, Disha Gupta, Naman Malhotra Journal of Anaesthesiology Clinical Pharmacology.2026; 42(1): 120. CrossRef
Hyperlipidemia exacerbates frozen shoulder fibrosis by activating the TGF-β/Smad2/3 signaling pathway via the TBX5-TNC-Itgα2 axis Fan Jiang, Yi Zhang, Jinlong Ma, Tengbo Yu, Youliang Shen iScience.2026; 29(2): 114660. CrossRef
Axillary recess capsular edema is associated with heterogeneity in rehabilitation response: Implications for a magnetic resonance imaging-based stratified treatment strategy for adhesive capsulitis De-Ting Zhu, Yan-Qi Shan, Yan Wang, ChenChen, Da-Dong Zhang, Xiu-Li Kan, Quan-Bing Zhang, Xue-Ming Li, Yun Zhou Archives of Physical Medicine and Rehabilitation.2026;[Epub] CrossRef
Clinical efficacy of Mulligan mobilization with movement versus proprioceptive neuromuscular facilitation on pain reduction and shoulder mobility in patients with frozen shoulder Sylejman Miftari, Mejdi Aliu Health, sport, rehabilitation.2026;[Epub] CrossRef