Objective
To elucidate the effect of task-specific lower extremity training (TSLET) on cognitive and gait function in stroke patients.
Methods
Thirty-eight patients were assigned to either the TSLET group or the control group. The individuals of TSLET group went through a TSLET plus conventional physical therapy. The control group received two sessions of conventional physical therapy. The primary outcome involved the assessment with visual and auditory digit span test. The secondary outcome was evaluated by the Korean version of Mini-Mental State Examination (K-MMSE) and Global Deterioration Scale (GDS) for cognitive function, Berg Balance Scale (BBS), Time Up and Go Test (TUG), 10 meters Walking Test (10mWT), 6 minutes Walking Test (6MWT), and Korean version of Modified Barthel Index (K-MBI) for gait, balance, and functional ability.
Results
After intervention (3 weeks) and 2 weeks of follow-up, the TSLET group showed statistically significant improvement in the visual digit span test backwards compared with the control group. In secondary outcome, a significant improvement was observed in GDS, BBS, TUG, and 10mWT in the TSLET group. There was no significant difference between the two groups concerning visual digit span test forward, auditory forward and backward digit span tests, K-MMSE, 6MWT, and K-MBI.
Conclusion
TSLET could be a useful alternative strategy for improving cognitive and gait function in stroke patients.

Citations

• The impact of different exercises on the short-distance activity capacity of stroke patients: a network meta-analysis
  Huan Niu, Zhikai Qin, Jiajun Lan, Renyi Liu, Shuya Chen, Junsheng Wang
  Journal of Public Health.2026;[Epub]     CrossRef
• Rehabilitation interventions for cognitive deficits in stroke survivors: A systematic review of randomized controlled trials
  Anas R. Alashram, Giuseppe Annino, Elvira Padua
  Applied Neuropsychology: Adult.2025; 32(1): 262.     CrossRef
• Effectiveness of balance training using the balance pro (SBT-330) device in patients with reduced balance ability following a stroke: Randomized controlled trial
  Jung-Lim Lee, Ji Hong Min, Sung-Hwa Ko, Hyunji Hwang, Ji Soo Baik, In Jae Park, Yeon Chul Lee, Jong Hwa Shin, Ki Jin Hwang, Chul Hyun Kim, Yong-Il Shin
  Journal of Bodywork and Movement Therapies.2025; 42: 381.     CrossRef
• Design, development, and validation of a non-backdrivable active ankle-foot orthosis for the TWIN lower-limb exoskeleton
  Raffaele Giannattasio, Nicolò Boccardo, Riccardo Vaccaro, Heeral Bhatt, Stefano Maludrottu, Elena De Momi, Matteo Laffranchi
  Frontiers in Robotics and AI.2025;[Epub]     CrossRef
• Effect of Different Exercises on the Gait Ability of Stroke Patients: A Network Meta-Analysis
  Yuxin He, Zhikai Qin, Huan Niu, Fei Gao, Qing Liu, Jialong Bu, Junsheng Wang
  Journal of Manipulative and Physiological Therapeutics.2025; 48(6-9): 631.     CrossRef
• Inclusion of People With Aphasia in Stroke Trials: A Systematic Search and Review
  Ciara Shiggins, Brooke Ryan, Farhana Dewan, Julie Bernhardt, Robyn O'Halloran, Emma Power, Richard I. Lindley, Gordon McGurk, Miranda L. Rose
  Archives of Physical Medicine and Rehabilitation.2024; 105(3): 580.     CrossRef
• Therapeutic Effects of a Newly Developed 3D Magnetic Finger Rehabilitation Device in Subacute Stroke Patients: A Pilot Study
  Sung-Hoon Kim, Dong-Min Ji, Chan-Yong Kim, Sung-Bok Choi, Min-Cheol Joo, Min-Su Kim
  Brain Sciences.2022; 12(1): 113.     CrossRef
• Effects of Action Observation Training Combied with Auditory Cueing on Gait Ability in Patients with Stroke: a Preliminary Pilot Study
  Hyeong-Min Kim, Sung-Min Son, Yu-Min Ko
  The Journal of Korean Physical Therapy.2022; 34(3): 98.     CrossRef
• Engagement in rehabilitation therapy and functional outcomes among individuals with acquired brain injuries
  Michael W. Williams, Lisa J. Rapport, Robin A. Hanks, Hillary A. Parker
  Disability and Rehabilitation.2021; 43(1): 33.     CrossRef
• Therapeutic Efficacy of Transcutaneous Electrical Nerve Stimulation Acupoints on Motor and Neural Recovery of the Affected Upper Extremity in Chronic Stroke: A Sham-Controlled Randomized Clinical Trial
  Reem M. Alwhaibi, Noha F. Mahmoud, Hoda M. Zakaria, Walaa M. Ragab, Nisreen N. Al Awaji, Mahmoud Y. Elzanaty, Hager R. Elserougy
  Healthcare.2021; 9(5): 614.     CrossRef
• Poststroke cognitive impairment and the possibility of its nonpharmacological treatment with vestibular stimulation based on biological feedback to supporting reaction
  S. V. Kotov, E. V. Isakova, E. V. Zaitseva
  Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova.2020; 120(3): 16.     CrossRef

Objective
To evaluate the usefulness of the quantitative assessment of pain perception (QAPP) in diabetic polyneuropathy (DPN) patients.
Methods
Thirty-two subjects with DPN were enrolled in this study. The subjects’ pain perception was assessed quantitatively. Current perception threshold (CPT) and pain equivalent current (PEC) were recorded. All patients were tested with a nerve conduction study (NCS) for evaluation of DPN and pain-related evoked potential (PREP) for evaluation of small fiber neuropathy (SFN) on bilateral upper and lower limbs. All patients were asked to participate in tests such as visual analogue scale (VAS) and SF-36 Health Survey Version 2 to evaluate their subjective pain and quality of life, respectively.
Results
The PEC of QAPP showed significant correlations with VAS (p=0.002) and physical function surveyed with SF-36 Health Survey Version 2 (p=0.035). The results of QAPP had no correlation with NCS, but there was a significant relationship between the CPT of QAPP and PREP (p=0.003).
Conclusion
The QAPP may be useful not only in providing objective evaluations of subjective pain in patients with DPN but also in the assessment of diabetic SFN.

Citations

• Structural Nerve Remodeling at 3-T MR Neurography Differs between Painful and Painless Diabetic Polyneuropathy in Type 1 or 2 Diabetes
  Johann M. E. Jende, Jan B. Groener, Zoltan Kender, Christian Rother, Artur Hahn, Tim Hilgenfeld, Alexander Juerchott, Fabian Preisner, Sabine Heiland, Stefan Kopf, Peter Nawroth, Martin Bendszus, Felix T. Kurz
  Radiology.2020; 294(2): 405.     CrossRef
• Effect of Topical Capsaicin on Painful Sensory Peripheral Neuropathy in Patients with Type 2 Diabetes: A Double-Blind Placebo-Controlled Randomised Clinical Trial
  Batakeh Ba Agoons, Mesmin Dehayem Yefou, Jean-Claude Katte, Martine Claude Etoa Etoga, Dayawa D Agoons, Faustin Yepnjio, Anne Boli, Yves Wasnyo, Eugene Sobngwi, Jean-Claude Mbanya
  Cureus.2020;[Epub]     CrossRef