Objective To investigate functional outcomes after the application of a critical pathway for inpatient rehabilitation of total knee arthroplasty (TKA).
Methods A total of 184 patients (57 males and 127 females; average age, 71.5±5.9 years) who underwent unilateral or bilateral TKA were included. The critical pathway included early, intensive individualized rehabilitation exercises. Patients completed the following performance-based physical function tests: the stair climbing test (SCT), 6-minute walk test (6MWT), and Timed Up and Go test (TUG) as well as measurement of isometric knee flexor and extensor strength of the operated knee, gait speed, and range of knee flexion and extension. Self-reported physical function and pain were measured using the Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) and visual analog scale (VAS), respectively, and self-reported quality of life was measured using the EuroQoL 5 dimension (EQ-5D) questionnaire. These evaluations were performed preoperatively and at 1 month and 3 months postoperatively.
Results Performance-based and self-reported physical function and quality of life measures improved nonlinearly over time. Specifically, the 6WMT, TUG, gait speed, WOMAC-pain, WOMAC-function, VAS, and EQ-5D scores showed a significant improvement at 1-month post-TKA, whereas SCT, peak torque of the knee extensors and flexors, and WOMAC-stiffness scores showed gradual, but substantial, improvements over 3 months. There were between-group differences (unilateral and bilateral TKA groups) in the time course of the SCT, 6MWT, TUG, VAS, WOAMC-stiffness, and WOMAC-function results.
Conclusion Patients who underwent critical pathway rehabilitation after TKA showed significant improvements in functional measurements during the first 3 months post-surgery.
Citations
Citations to this article as recorded by
Comparison of postural stability and Romberg quotient before and after total knee arthroplasty in individuals with knee osteoarthritis Saidan Shetty, G. Arun Maiya, Mohandas Rao KG, Sandeep Vijayan, Shetty Shrija Jaya, Bincy M. George Disability and Rehabilitation.2026; : 1. CrossRef
Exercise with blood flow restriction among adults undergoing total knee arthroplasty: A scoping review Nelson Viscay-Sanhueza, Cristian Curilem Gatica, Carlos Bahamondes-Avila Journal of Bodywork and Movement Therapies.2025; 42: 665. CrossRef
The effect of preoperative education on fear of first mobilization experienced after total knee arthroplasty in individuals Ayşegül Kaya İmrek, Meryem Yilmaz International Journal of Orthopaedic and Trauma Nursing.2025; 57: 101189. CrossRef
Effectiveness of muscle strengthening in early postoperative total knee arthroplasty: systematic review with meta-analysis Alany Gabrielli Leite, Beatriz Batista Vicente, Alessandra Madia Mantovani, Allysiê Priscilla de Souza Cavina Fisioterapia e Pesquisa.2025;[Epub] CrossRef
Eficácia do fortalecimento muscular no pós-operatório precoce de artroplastia total do joelho: revisão sistemática com metanálise Alany Gabrielli Leite, Beatriz Batista Vicente, Alessandra Madia Mantovani, Allysiê Priscilla de Souza Cavina Fisioterapia e Pesquisa.2025;[Epub] CrossRef
Kinesiophobia and Pain Coping on Patients with Gonarthrosis: Postoperative Pain and Mobility Tevfik Şenol, Sevim Çelik Pain Management Nursing.2025;[Epub] CrossRef
Recovery of gait speed and timed up and go test in three weeks after total knee arthroplasty Akira Iwata, Yuki Sano, Hideyuki Wanaka, Shingo Kobayashi, Kensuke Okamoto, Jun Yamahara, Masaki Inaba, Yuya Konishi, Junji Inoue, Atsuki Kanayama, Saki Yamamoto, Hiroshi Iwata European Journal of Physiotherapy.2024; 26(5): 256. CrossRef
The real results of total knee arthroplasty in moderate-to-severe osteoarthritis: a 1-year cohort study André F. CANELAS, Paulo C. ARAÚJO, Raquel P. FONSECA, José B. FERREIRA, Simão E. SERRANO, Maria L. LUÍS, Filipa S. JANUÁRIO, Ana M. BÁRTOLO Minerva Orthopedics.2022;[Epub] CrossRef
Establishment of a qualified integrated care system after total knee arthroplasty as a role of regional rheumatoid and degenerative arthritis centers Eun Young Han, Sang Rim Kim, Kye Hee Cho, Sang Hee Im BMC Geriatrics.2022;[Epub] CrossRef
Comparison of simultaneous bilateral versus unilateral total knee replacement on pain levels and functional recovery Ahmad H. Alghadir, Zaheen A. Iqbal, Shahnawaz Anwer, Dilshad Anwar BMC Musculoskeletal Disorders.2020;[Epub] CrossRef
Physical Performance Correlates with Self-Reported Physical Function and Quality of Life in Patients at 3 Months after Total Knee Arthroplasty Jun Hwan Choi, Bo Ryun Kim, Sang Rim Kim, Kwang Woo Nam, So Young Lee, Won Bin Kim, Youn Ji Kim Annals of Geriatric Medicine and Research.2020; 24(2): 99. CrossRef
Objective To determine post-operative physical performance factors associated with gait speed in patients surgically treated for hip fracture.
Methods Cross-sectional data from 59 patients (16 males and 43 females; mean age, 79.2±9.1 years) who underwent hip fracture surgery were enrolled. Patients completed a 10-meter walk test (10MWT) to assess gait speed. Additional physical performance tests included the Timed Up and Go test (TUG), the Berg Balance Scale (BBS), maximum voluntary isometric contraction (MVIC) of the knee extensors and flexors on the operated and non-operated sides as well as of the hip abductors (all tested using air-resistance weight machines), and analysis of spatio-temporal gait parameters at about 6 weeks after hip surgery.
Results Bivariate analyses revealed a significant positive correlation between the post-operative 10MWT and the post-operative TUG, age, swing phase duration, and gait cycle duration along with a significant negative correlation between post-operative BBS score, MVIC of the knee extensors and flexors on the operated and non-operated sides, MVIC of the hip abductors, and cadence and stance phase duration. Linear regression analyses revealed that the post-operative TUG (β=0.85, p<0.01), gait cycle duration (β=0.17, p=0.02), and osteoporosis (β=-0.18, p=0.02) were associated with the post-operative 10MWT.
Conclusion The presence of osteoporosis, post-operative balance, and isometric muscle strength in the operated and non-operated legs were statistically associated with post-operative gait speed early after hip fracture surgery.
Citations
Citations to this article as recorded by
Association of surgical procedure and radiographic hip alignment with hip abductor strength ratio at discharge after proximal femoral fracture surgery Satoshi Hakukawa, Shunsuke Onuma, Kanata Yoshihara Journal of Orthopaedics.2026; 74: 131. CrossRef
Can Patients Self-Identify Gait Disturbances After Lower Extremity Trauma? Enhancing Patient Engagement in Their Care Tyler Forbes, Joseph Cavataio, Andrew Robinson, Abdel Kareem Hilo, Alyxandra Camello, Anagha Purushotham, Rahul Vaidya Journal of Clinical Medicine.2026; 15(3): 1175. CrossRef
Virtual reality-enhanced rehabilitation for improving musculoskeletal function and recovery after trauma Phani Paladugu, Rahul Kumar, Joshua Ong, Ethan Waisberg, Kyle Sporn Journal of Orthopaedic Surgery and Research.2025;[Epub] CrossRef
The Impact of Total Hip Arthroplasty on Daily Ambulatory Function: A Prospective Study Kevin A. Wu, Eric S. Dilbone, David N. Kugelman, Rahul K. Goel, Sean P. Ryan, Samuel S. Wellman, Michael P. Bolognesi, Thorsten M. Seyler The Journal of Arthroplasty.2025; 40(9): S253. CrossRef
Clinical Impact of Neuropostural and Neuromuscular Optimization Protocols With Radio Electric Asymmetric Conveyer (REAC) Technology in Older Adults With Femoral Fractures: An Observational Study Bruna Lombardi, Margherita Imbrenda, Valtere Giovannini, Vania Fontani, Salvatore Rinaldi Cureus.2025;[Epub] CrossRef
Markerless three-dimensional gait analysis in healthy older adults: test–retest reliability and measurement error Andreia Carvalho, Jos Vanrenterghem, Sílvia Cabral, Ana Assunção, Rita Fernandes, António P. Veloso, Vera Moniz-Pereira Journal of Biomechanics.2024; 174: 112280. CrossRef
Balancing act: Unraveling the link between muscle strength, proprioception, and stability in unilateral hip osteoarthritis Batool Abdulelah Alkhamis, Ravi Shankar Reddy, Khalid A. Alahmari, Mastour Saeed Alshahrani, Ghada Mohammed Koura, Olfat Ibrahim Ali, Debjani Mukherjee, Basant Hamdy Elrefaey, Holakoo Mohsenifar PLOS ONE.2024; 19(2): e0298625. CrossRef
Association of Nutritional Risk With Gait Function and Activities of Daily Living in Older Adult Patients With Hip Fractures Yasunobu Ishikawa, Takuji Adachi, Yasushi Uchiyama Annals of Rehabilitation Medicine.2024; 48(2): 115. CrossRef
Quantified clinical measures linked to ambulation speed in hemiparesis Mouna Ghédira, Maud Pradines, Valentina Mardale, Jean-Michel Gracies, Nicolas Bayle, Emilie Hutin Topics in Stroke Rehabilitation.2022; 29(6): 411. CrossRef
Minimal clinically important difference of the Berg Balance Scale score in older adults with hip fractures Shuntaro Tamura, Kazuhiro Miyata, Sota Kobayashi, Ren Takeda, Hiroki Iwamoto Disability and Rehabilitation.2022; 44(21): 6432. CrossRef
Mechanisms for increased systemic fracture risk after index fracture B. Osipov, B.A. Christiansen Medicine in Novel Technology and Devices.2021; 11: 100072. CrossRef
Impact of Bone Fracture on Muscle Strength and Physical Performance—Narrative Review Pawel Szulc Current Osteoporosis Reports.2020; 18(6): 633. CrossRef