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"Ki Hoon Lee"

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"Ki Hoon Lee"

Original Articles
Influence of Low Peak Respiratory Exchange Ratio on Cardiac Rehabilitation in Patients With Coronary Artery Disease
Chul Kim, Hee Eun Choi, Ki Hoon Lee, Young Joo Kim, Sang Jae Lee
Ann Rehabil Med 2016;40(6):1114-1123.   Published online December 30, 2016
DOI: https://doi.org/10.5535/arm.2016.40.6.1114
Objective

To compare and analyze the effects of cardiac rehabilitation (CR) in two groups based on the peak respiratory exchange ratio (RERpeak) 1.1 values using the exercise tolerance test (ETT) results, and to investigate the reasons for early termination of ETT.

Methods

Patients with acute coronary syndrome who participated in CR exercise training were selected and all subjects underwent 6 weeks of CR exercise training. ETT was performed on a treadmill using a Modified Bruce Protocol before and after CR exercise training. According to the result of the first ETT, the subjects were divided into two groups: those with an RERpeak≥1.1 (n=33) and those with an RERpeak<1.1 (n=22). We investigated the reasons for ETT termination and compared the effect of CR between the groups.

Results

The reasons for the early termination of the first ETT in the RERpeak<1.1 group were subjective dyspnea, abnormal cardiovascular responses, leg fatigue and other problems. After a 6-week CR, the peak oxygen consumption (VO2peak) and ETT time increased, and the rate of perceived exertion (RPE) and RPP (rate pressure product) at stage 3 decreased in both the RERpeak<1.1 and RERpeak≥1.1 groups.

Conclusion

CR exercise training improved exercise capacity, not only in the RERpeak≥1.1 group, but also in the RERpeak<1.1 group. This means that patients with a lower exercise tolerance could also benefit from the effects of CR. Thoughtful consideration to identify the direct and indirect causes for the early termination of ETT would be necessary to improve the efficiency of CR.

Citations

Citations to this article as recorded by  
  • The effects of acute bouts of exercise in fasted vs. fed states on glucose and lipid metabolism in healthy adults: A systematic review and meta-analysis of randomized clinical trials
    Fatemeh Kazeminasab, Pegah Rafiee, Maryam Miraghajani, Heitor O. Santos, Michael E. Symonds, Sara K. Rosenkranz
    Clinical Nutrition ESPEN.2025; 66: 320.     CrossRef
  • Exercise intolerance associated with impaired oxygen extraction in patients with long COVID
    Anna Norweg, Lanqiu Yao, Scott Barbuto, Anna S. Nordvig, Thaddeus Tarpey, Eileen Collins, Jonathan Whiteson, Greg Sweeney, Francois Haas, John Leddy
    Respiratory Physiology & Neurobiology.2023; 313: 104062.     CrossRef
  • Enhancing Cardiovascular Health and Functional Recovery in Stroke Survivors: A Randomized Controlled Trial of Stroke-Specific and Cardiac Rehabilitation Protocols for Optimized Rehabilitation
    Moattar Raza Rizvi, Ankita Sharma, Ahmed Malki, Waqas Sami
    Journal of Clinical Medicine.2023; 12(20): 6589.     CrossRef
  • Relationship Between Number of Cardiac Rehabilitation Exercise Training Sessions, Muscle Mass, and Cardiorespiratory Fitness in Rural Elderly Patients with Coronary Artery Disease
    Seong Bok Choi, Ji Hee Kim
    Journal of Multidisciplinary Healthcare.2023; Volume 16: 3309.     CrossRef
  • Characteristics and Safety of Cardiopulmonary Exercise Testing in Elderly Patients with Cardiovascular Diseases in Korea
    Bong-Joon Kim, Youngju Kim, Jaewon Oh, Jihun Jang, Seok-Min Kang
    Yonsei Medical Journal.2019; 60(6): 547.     CrossRef
  • Improvements in Key Cardiopulmonary Exercise Testing Variables Following Cardiac Rehabilitation in Patients With Coronary Artery Disease
    Dejana Popovic, Nikhil Kumar, Sundeep Chaudhry, Akshay Bagai, Ross Arena, Naresh Kumar
    Journal of Cardiopulmonary Rehabilitation and Prevention.2018; 38(5): E5.     CrossRef
  • 7,969 View
  • 83 Download
  • 6 Web of Science
  • 6 Crossref
Objective

To investigate the efficacy of percutaneous adhesiolysis (PA) compared to fluoroscopy (FL)-guided transforaminal epidural steroid injection (TFESI) in patients with radicular pain caused by lumbar foraminal spinal stenosis (LFSS) by assessing pain relief and functional improvement at 4 and 12 weeks post-procedure.

Methods

This retrospective study included 45 patients who underwent PA or FL-guided TFSEI for radicular pain caused by LFSS of at least 3 months' duration. Outcomes were assessed with the Oswestry Disability Index (ODI) and Verbal Numeric Pain Scale (VNS) before the procedure and at 4 and 12 weeks post-procedure. A successful outcome was defined by >50% improvement in the VNS score and >40% improvement in the ODI score.

Results

ODI and VNS scores improved 4 and 12 weeks post-procedure in both groups. Statistically significant differences between groups were observed in ODI and VNS at 12 weeks (p<0.05). The proportion of patients with successful outcomes was significantly different between the two groups only at the 12-week time point.

Conclusion

Our study suggests that PA is effective for pain reduction and functional improvement in patients with chronic radicular pain caused by LFSS. Therefore, PA can be considered for patients with previous ineffective responses to conservative treatment. Although PA seems to be more effective than TFEFI according to the results of our study, in order to fully elucidate the difference in effectiveness, a prospective study with a larger sample size is necessary.

Citations

Citations to this article as recorded by  
  • Efficacy of High-Voltage Pulsed Radiofrequency of the Dorsal Root Ganglion for Treatment of Chronic Lumbosacral Radicular Pain: A Randomized Clinical Trial
    Burak Erken, Ipek S. Edipoglu
    Neuromodulation: Technology at the Neural Interface.2024; 27(1): 135.     CrossRef
  • The Short-Term Outcome of Transforaminal Epidural Steroid Injection in Patients with Radicular Pain Due to Foraminal Stenosis from Lumbar Isthmic Spondylolisthesis
    Gyu-Sik Choi, Mathieu Boudier-Revéret, Min Cheol Chang
    Journal of Pain Research.2024; Volume 17: 519.     CrossRef
  • Evaluation of Fluoroscopically Guided Transforaminal Selective Nerve Root Sleeve Injections for Lumbar Spinal Stenosis With Radiculopathy Utilizing Patient Reported Outcome Measurement Information System as an Outcome Measure
    Andrew R. Stephens, Ramzi El-Hassan, Rajeev K. Patel
    Archives of Physical Medicine and Rehabilitation.2024; 105(8): 1458.     CrossRef
  • Transforaminal Steroid Injection After Dorsal Root Ganglion Pulsed Radiofrequency (DRG-PRF): Impact on Pain Intensity and Disability
    Matteo Luigi Giuseppe Leoni, Fabrizio Micheli, David Michael Abbott, Marco Cascella, Giustino Varrassi, Pasquale Sansone, Roberto Gazzeri, Monica Rocco, Marco Mercieri
    Pain and Therapy.2024; 13(5): 1271.     CrossRef
  • Changes in pain scores and walking distance after transforaminal epidural steroid injection in patients with lumbar foraminal spinal stenosis
    Minsoo Kim, Jiwon Bak, Daehun Goh, Jangho Bae, Kiyoung Shin, Hee-Jeong Son, Jin Huh, Seong-Sik Kang, Byeongmun Hwang
    Medicine.2023; 102(25): e34032.     CrossRef
  • Spinal Injections: A Narrative Review from a Surgeon’s Perspective
    Dong Ah Shin, Yoo Jin Choo, Min Cheol Chang
    Healthcare.2023; 11(16): 2355.     CrossRef
  • Predictive Factors Associated with Successful Response to Percutaneous Adhesiolysis in Chronic Lumbar Radicular Pain
    Halil Cihan Kose, Omer Taylan Akkaya
    Journal of Clinical Medicine.2023; 12(19): 6337.     CrossRef
  • Contralateral retrodiscal transforaminal approach for percutaneous epidural adhesiolysis: A technical description and retrospective comparative study
    Ki‐Han You, Hyun‐Jin Park, In‐Seok Son, Hoon‐Jae Chung, Min‐Seok Kang
    Pain Practice.2022; 22(4): 424.     CrossRef
  • Do steroid injections to the peripheral nerve increase perineural fibrosis? An animal experimental study
    Mustafa ÇELİKTAŞ, Semih Kivanc OLGUNER, Kivilcim ERDOGAN, Remzi ÇAYLAK, Kenan DAĞLIOĞLU
    Journal of Surgery and Medicine.2022; 6(2): 181.     CrossRef
  • The Effectiveness of Lumbar Transforaminal Injection of Steroid for the Treatment of Radicular Pain: A Comprehensive Review of the Published Data
    Clark C Smith, Zachary L McCormick, Ryan Mattie, John MacVicar, Belinda Duszynski, Milan P Stojanovic
    Pain Medicine.2020; 21(3): 472.     CrossRef
  • Electrocatheter-mediated High-voltage Pulsed Radiofrequency of the Dorsal Root Ganglion in the Treatment of Chronic Lumbosacral Neuropathic Pain
    Simone Vigneri, Gianfranco Sindaco, Marco La Grua, Matteo Zanella, Giuliano Lo Bianco, Valentina Paci, Francesca M. Vinci, Chiara Sciacca, Laura Ravaioli, Gilberto Pari
    The Clinical Journal of Pain.2020; 36(1): 25.     CrossRef
  • At Least 5‐Year Follow‐up After Transforaminal Epidural Steroid Injection Due to Lumbar Radicular Pain Caused by Spinal Stenosis
    Seung Hwa Jang, Min Cheol Chang
    Pain Practice.2020; 20(7): 748.     CrossRef
  • Lumbar foraminal neuropathy: an update on non-surgical management
    Young Kook Choi
    The Korean Journal of Pain.2019; 32(3): 147.     CrossRef
  • Effectiveness of Percutaneous Lumbar Extraforaminotomy in Patients with Lumbar Foraminal Spinal Stenosis: A Prospective, Single-Armed, Observational Pilot Study
    Sang Chul Lee, Won-Joong Kim, Chang-Soon Lee, Jee Youn Moon
    Pain Medicine.2017; 18(10): 1975.     CrossRef
  • The Prognostic Value of Enhanced-MRI and Fluoroscopic Factors for Predicting the Effects of Transforaminal Steroid Injections on Lumbosacral Radiating Pain
    Yun Suk Jung, Jee Hyun Suh, Ha Young Kim, Kyunghoon Min, Yoongul Oh, Donghwi Park, Ju Seok Ryu
    Annals of Rehabilitation Medicine.2016; 40(6): 1071.     CrossRef
  • 10,282 View
  • 81 Download
  • 17 Web of Science
  • 15 Crossref
Comparison of the Effects of 1 Hz and 20 Hz rTMS on Motor Recovery in Subacute Stroke Patients
Chul Kim, Hee Eun Choi, Heejin Jung, Byeong-Ju Lee, Ki Hoon Lee, Young-Joon Lim
Ann Rehabil Med 2014;38(5):585-591.   Published online October 30, 2014
DOI: https://doi.org/10.5535/arm.2014.38.5.585
Objective

To compare the low frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) with high frequency (20 Hz) rTMS on motor functional improvement of the affected upper extremity in subacute stroke patients.

Methods

Forty patients with subacute ischemic stroke participated in this study. The first group received 10 sessions of 20 Hz rTMS at ipsilesional M1 area and the other group received 10 sessions of 1 Hz rTMS at contralesional M1 area. Motor training of the hemiparetic hand was conducted after each rTMS train. All the patients received conventional occupational therapy immediately after each rTMS session. Manual function test (MFT), Fugl-Meyer Assessment scale (FMS), Modified Barthel Index (MBI), Brunnstrom recovery stage, and grip strength were used to assess motor function before, at the end of, and one month after the last session of rTMS.

Results

No adverse side effects were reported during the course of the experiment using rTMS. No significant difference in motor function of the affected upper extremity was observed between the two groups before rTMS. Significant improvements in MFT, FMS, MBI, and Brunnstrom stage were observed in the both groups at the end of the last rTMS session and one month later (p<0.05). No significant difference was found between the two groups (p>0.05).

Conclusion

There was no significant difference in motor function of the affected upper extremity between 1 Hz and 20 Hz rTMS during the subacute period of ischemic stroke. Thus, we cannot conclude which has a greater effect.

Citations

Citations to this article as recorded by  
  • Effect of low-frequency repetitive transcranial magnetic stimulation combined with abdominal acupuncture on lower limb motor function and balance in post-stroke hemiplegia: a randomized controlled trial
    Chaobing Zhang, Shixin Qin, Xiuyuan Wang, Li Shu, Xueping Dong
    Frontiers in Neurology.2026;[Epub]     CrossRef
  • Observing the Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation Combined with Scalp Acupuncture Therapy on Hand Dysfunction after Stroke
    克伟 张
    Advances in Clinical Medicine.2025; 15(03): 513.     CrossRef
  • Repetitive transcranial magnetic stimulation and constraint-induced movement therapy combined in the treatment of post-stroke movement disorders: a narrative review
    Zhennan Liu, Qingying Yu, Feng Zhou, Muyao Yu, Huan Shu, Manhua Zhu, Tianzhong Peng
    Frontiers in Human Neuroscience.2025;[Epub]     CrossRef
  • A meta-analysis of the effects of transcranial magnetic stimulation on hand function and daily living ability after stroke
    Yue Shen, Jinchao Du, Xiaoduo Yao, Jiqin Tang
    Medicine.2025; 104(35): e44029.     CrossRef
  • Neuromodulatory Responses Elicited by Intermittent versus Continuous Transcranial Focused Ultrasound Stimulation of the Motor Cortex in Rats
    Tsung-Hsun Hsieh, Po-Chun Chu, Thi Xuan Dieu Nguyen, Chi-Wei Kuo, Pi-Kai Chang, Kai-Hsiang Stanley Chen, Hao-Li Liu
    International Journal of Molecular Sciences.2024; 25(11): 5687.     CrossRef
  • Effects of Extremely Low-Frequency Electromagnetic Field Treatment on ASD Symptoms in Children: A Pilot Study
    Kierra Pietramala, Alessandro Greco, Alberto Garoli, Danielle Roblin
    Brain Sciences.2024; 14(12): 1293.     CrossRef
  • Applications of Repetitive Transcranial Magnetic Stimulation to Improve Upper Limb Motor Performance After Stroke: A Systematic Review
    Afifa Safdar, Marie-Claire Smith, Winston D. Byblow, Cathy M. Stinear
    Neurorehabilitation and Neural Repair.2023; 37(11-12): 837.     CrossRef
  • Evaluation of Contralateral Limb Cross Education and High-Frequency Repetitive Transcranial Magnetic Stimulation on Functional Indices of the Affected Upper Limb in Subacute Phase of Stroke
    Katayoon Rezaei, Amin Kordi Yoosefinejad, Farzaneh Moslemi Haghighi, Mohsen Razeghi, Anwen Shao
    Stroke Research and Treatment.2023; 2023: 1.     CrossRef
  • Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized Controlled Study
    Ka Yan Luk, Hui Xi Ouyang, Marco Yiu Chung Pang, Takashi Hanakawa
    Neural Plasticity.2022; 2022: 1.     CrossRef
  • Repetitive transcranial magnetic stimulation modulates cortical–subcortical connectivity in sensorimotor network
    Jing Chen, Yanzi Fan, Wei Wei, Luoyu Wang, Xiaoyu Wang, Fengmei Fan, Zejuan Jia, Mengting Li, Jinhui Wang, Qihong Zou, Bing Chen, Yating Lv
    European Journal of Neuroscience.2022; 55(1): 227.     CrossRef
  • Repetitive transcranial magnetic stimulation for upper limb motor function and activities of daily living in patients with stroke: a protocol of a systematic review and Bayesian network meta-analysis
    Yue Lu, Yuan Xia, Yue Wu, Xinyong Pan, Zhenyu Wang, Yongjie Li
    BMJ Open.2022; 12(3): e051630.     CrossRef
  • Short-Term Immobilization Promotes a Rapid Loss of Motor Evoked Potentials and Strength That Is Not Rescued by rTMS Treatment
    Christopher J. Gaffney, Amber Drinkwater, Shalmali D. Joshi, Brandon O'Hanlon, Abbie Robinson, Kayle-Anne Sands, Kate Slade, Jason J. Braithwaite, Helen E. Nuttall
    Frontiers in Human Neuroscience.2021;[Epub]     CrossRef
  • Physiology of Cerebellar Reserve: Redundancy and Plasticity of a Modular Machine
    Hiroshi Mitoma, Shinji Kakei, Kazuhiko Yamaguchi, Mario Manto
    International Journal of Molecular Sciences.2021; 22(9): 4777.     CrossRef
  • Corticomotor Plasticity Predicts Clinical Efficacy of Combined Neuromodulation and Cognitive Training in Alzheimer’s Disease
    Anna-Katharine Brem, Riccardo Di Iorio, Peter J. Fried, Albino J. Oliveira-Maia, Camillo Marra, Paolo Profice, Davide Quaranta, Lukas Schilberg, Natasha J. Atkinson, Erica E. Seligson, Paolo Maria Rossini, Alvaro Pascual-Leone
    Frontiers in Aging Neuroscience.2020;[Epub]     CrossRef
  • The Use of Repetitive Transcranial Magnetic Stimulation for Stroke Rehabilitation: A Systematic Review
    Ana Dionísio, Isabel Catarina Duarte, Miguel Patrício, Miguel Castelo-Branco
    Journal of Stroke and Cerebrovascular Diseases.2018; 27(1): 1.     CrossRef
  • Combined rTMS and virtual reality brain–computer interface training for motor recovery after stroke
    N N Johnson, J Carey, B J Edelman, A Doud, A Grande, K Lakshminarayan, B He
    Journal of Neural Engineering.2018; 15(1): 016009.     CrossRef
  • Cerebellar Cortex as a Therapeutic Target for Neurostimulation
    Kim van Dun, Hiroshi Mitoma, Mario Manto
    The Cerebellum.2018; 17(6): 777.     CrossRef
  • Effectiveness of repetitive transcranial magnetic stimulation (rTMS) after acute stroke: A one‐year longitudinal randomized trial
    Yu‐Zhou Guan, Jing Li, Xue‐Wei Zhang, Shuang Wu, Hua Du, Li‐Ying Cui, Wei‐Hong Zhang
    CNS Neuroscience & Therapeutics.2017; 23(12): 940.     CrossRef
  • Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis
    Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu
    Neural Plasticity.2017; 2017: 1.     CrossRef
  • Effects of low-frequency repetitive transcranial magnetic stimulation and neuromuscular electrical stimulation on upper extremity motor recovery in the early period after stroke: a preliminary study
    Aliye Tosun, Sabiha Türe, Ayhan Askin, Engin Ugur Yardimci, Secil Umit Demirdal, Tülay Kurt Incesu, Ozgur Tosun, Hikmet Kocyigit, Galip Akhan, Fazıl Mustafa Gelal
    Topics in Stroke Rehabilitation.2017; 24(5): 361.     CrossRef
  • Role of the Contralesional vs. Ipsilesional Hemisphere in Stroke Recovery
    Keith C. Dodd, Veena A. Nair, Vivek Prabhakaran
    Frontiers in Human Neuroscience.2017;[Epub]     CrossRef
  • Effects of different frequencies of repetitive transcranial magnetic stimulation on the recovery of upper limb motor dysfunction in patients with subacute cerebral infarction
    Jiang Li, Xiang-min Meng, Ru-yi Li, Ru Zhang, Zheng Zhang, Yi-feng Du
    Neural Regeneration Research.2016; 11(10): 1584.     CrossRef
  • Scalp acupuncture and electromagnetic convergence stimulation for patients with cerebral infarction: study protocol for a randomized controlled trial
    Jae-Young Han, Jae-Hong Kim, Ju-Hyung Park, Min-Yeong Song, Min-Keun Song, Dong-Joo Kim, Young-Nim You, Gwang-Cheon Park, Jin-Bong Choi, Myung-Rae Cho, Jeong-Cheol Shin, Ji-Hyun Cho
    Trials.2016;[Epub]     CrossRef
  • A Framework for Combining rTMS with Behavioral Therapy
    K. Zoe Tsagaris, Douglas R. Labar, Dylan J. Edwards
    Frontiers in Systems Neuroscience.2016;[Epub]     CrossRef
  • Factors Associated With Upper Extremity Functional Recovery Following Low-Frequency Repetitive Transcranial Magnetic Stimulation in Stroke Patients
    Seo Young Kim, Sung Bong Shin, Seong Jae Lee, Tae Uk Kim, Jung Keun Hyun
    Annals of Rehabilitation Medicine.2016; 40(3): 373.     CrossRef
  • Bursts of high-frequency repetitive transcranial magnetic stimulation (rTMS), together with lorazepam, suppress seizures in a rat kainate status epilepticus model
    Roman Gersner, Sameer C. Dhamne, Abraham Zangen, Alvaro Pascual-Leone, Alexander Rotenberg
    Epilepsy & Behavior.2016; 62: 136.     CrossRef
  • Effects of low- and high-frequency repetitive magnetic stimulation on neuronal cell proliferation and growth factor expression: A preliminary report
    Ji Yong Lee, Hyung Joong Park, Ji Hyun Kim, Byung Pil Cho, Sung-Rae Cho, Sung Hoon Kim
    Neuroscience Letters.2015; 604: 167.     CrossRef
  • 9,712 View
  • 88 Download
  • 26 Web of Science
  • 27 Crossref
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