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"Hyun Cheol Lee"

Case Report

Central Hyperthermia Treated With Baclofen for Patient With Pontine Hemorrhage
Hyun Cheol Lee, Jong Moon Kim, Jae Kuk Lim, Yoon Sik Jo, Shin Kyoung Kim
Ann Rehabil Med 2014;38(2):269-272.   Published online April 29, 2014
DOI: https://doi.org/10.5535/arm.2014.38.2.269

Central hyperthermia is a very rare disease; however, once it happens, it is associated with a poor prognosis and high mortality for patients with severe brainstem strokes. Following a pontine hemorrhage, a 46-years-old female developed prolonged hyperthermia. Work-ups to the fever gave no significant clues for the origin of fever, and hyperthermia did not respond to any empirical antibiotics or antipyretic agents. The patient's body temperature still fluctuated in a range of 37.5℃ to 39.2℃. Considering the lesion of hemorrhage, we suspected central hyperthermia rather than infectious diseases. We started with baclofen administration at a dose of 30 mg/day. The body temperature changed to a range of 36.6℃ to 38.2℃. We raised the dose of baclofen to 60 mg/day. The patient's body temperature finally dropped to a normal range. Central hyperthermia, caused by failures of thermoregulatory pathways in brainstem, following the pontine hemorrhage rarely occurs. Baclofen can be used to treat suspected central hyperthermia in a patient with pontine hemorrhage.

Citations

Citations to this article as recorded by  
  • Use of Baclofen for Neurogenic Fever in Head Injury Patients: A Case Series of Four Patients
    Dharmraj Singh, Mayank Sachan, Priyanka Gautam
    Journal of Trauma Intensive Care STIC.2025; 1(2): 32.     CrossRef
  • Postoperative fever following hemispherotomy managed with baclofen: unnoticed treatment
    Mohammad Elbaroody, Hossam Eldin Mostafa, Salsabil Abo Al-Azayem, Amani Nawito, Nirmeen A. Kishk, Basim Ayoub
    Child's Nervous System.2025;[Epub]     CrossRef
  • Pharmacologic Management of Central Fever: A Review of Evidence for Bromocriptine, Propranolol, and Baclofen
    Justin P. Reinert, Zsanett Kormanyos
    Journal of Pharmacy Technology.2023; 39(1): 29.     CrossRef
  • Central neurogenic hyperthermia
    Veronika Kissiová
    Neurologie pro praxi.2023; 24(3): 212.     CrossRef
  • Management of Central Hyperthermia in Traumatic Brain Injury Using Baclofen
    Ijaz N. Pillai, Gaurav Gomez
    Indian Journal of Physical Medicine and Rehabilitation.2023; 33(2): 83.     CrossRef
  • Use of baclofen and propranolol for treatment of neurogenic fever in a patient with pontine hemorrhage: A case report
    Saroj Poudel, Rupak Chalise, Manoj Bist, Ashim Regmi, Anup Ghimire, Kishor Khanal
    Clinical Case Reports.2023;[Epub]     CrossRef
  • Central Hyperthemia Treated with Bromocriptine in a Patient with Aquaporin 4 Antibody Positive Neuromyelitis Optica Spectrum Disorder
    Hayoung Choi, Ryeongtae Kim, Sooyoung Kim, Eunhee Sohn
    Journal of Multiple Sclerosis and Neuroimmunology.2023; 14(2): 106.     CrossRef
  • Primary Brainstem Hemorrhage: A Review of Prognostic Factors and Surgical Management
    Danyang Chen, Yingxin Tang, Hao Nie, Ping Zhang, Wenzhi Wang, Qiang Dong, Guofeng Wu, Mengzhou Xue, Yuping Tang, Wenjie Liu, Chao Pan, Zhouping Tang
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • Central Hyperthermia Due to Intracerebral Hemorrhage Treated with Baclofen: A Case Report
    Jiyong Iruon Park, Sung-Kyun Hwang
    The Nerve.2021; 7(2): 103.     CrossRef
  • Treating Paroxysmal Sympathetic Hyperactivity With Enteral Baclofen in Anoxic Brain Injury
    Lena M. O’Keefe, Gracia Mui
    The Neurologist.2020; 25(2): 24.     CrossRef
  • Early tracheostomy is associated with better prognosis in patients with brainstem hemorrhage
    Wei-Long Ding, Yong-Sheng Xiang, Jian-Cheng Liao, Shi-Yong Wang, Xiang-Yu Wang
    Journal of Integrative Neuroscience.2020;[Epub]     CrossRef
  • Baclofen for neurogenic fever in a patient with cerebral contusion
    Deep Sengupta, Indu Kapoor, Charu Mahajan, Hemanshu Prabhakar
    Journal of Clinical Anesthesia.2019; 55: 134.     CrossRef
  • Successful Intrathecal Baclofen Therapy for Intractable Paroxysmal Sympathetic Hyperactivity in Patient with Pontine Hemorrhage: A case report
    Hyeon Su Kim, Na Young Kim, Yong Wook Kim
    Clinical Neuropharmacology.2018; 41(4): 138.     CrossRef
  • Korean Medical Treatment for Prolonged Central Hyperthermia Following Pontine Hemorrhage: A Case Report
    Chan-sol Yi, Song-won Park, Seungcheol Hong, Youngji Kim, Juyeon Song, Jeong-yun Lee, Gil-cho Shin, Dong-jun Choi
    The Journal of Internal Korean Medicine.2018; 39(5): 1061.     CrossRef
  • Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures
    Claire F. Durant, Louise M. Paterson, Sam Turton, Susan J. Wilson, James F. M. Myers, Suresh Muthukumaraswamy, Ashwin Venkataraman, Inge Mick, Susan Paterson, Tessa Jones, Limon K. Nahar, Rosa E. Cordero, David J. Nutt, Anne Lingford-Hughes
    Frontiers in Psychiatry.2018;[Epub]     CrossRef
  • Central Hyperthermia Treated with Bromocriptine
    P. Natteru, P. George, R. Bell, P. Nattanmai, C. R. Newey
    Case Reports in Neurological Medicine.2017; 2017: 1.     CrossRef
  • 6,282 View
  • 81 Download
  • 12 Web of Science
  • 16 Crossref
Original Article
Analysis of Publication Status of Abstracts Presented at the Annual Meeting of the Korean Academy of Rehabilitation Medicine
Jae Kuk Lim, Jun Young Han, Hyun Cheol Lee, Jiwon Lee, Hong Chung, Jong Moon Kim, Shin Kyoung Kim
Ann Rehabil Med 2013;37(3):413-419.   Published online June 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.3.413
Objective

To analyze publication rate, time to publication and the characteristics of the abstracts presented at the annual Korean Academy of Rehabilitation Medicine (KARM) meetings.

Methods

A total of 1,027 abstracts presented at the 2008 and 2009 annual KARM meetings were enrolled in the database and searched for their subsequent citation in PubMed, KoreaMed, and Google Scholar.

Results

The data analysis revealed that 317 (30.87%) abstracts, were published as full-length journal articles and publication rates by subject were not significantly different. The mean time to publication was 17.17±10.48 months, and the journals written in English (20.39±10.20) required a longer duration than those written in Korean (11.94±8.44) with statistical significance (p<0.001). There was no statistical difference (p=0.284) in the duration between domestic (17.61±10.37) and foreign (16.48±10.51) of the 220 domestic journal articles, 190 (86.76%) were published in the Annals of Rehabilitation Medicine and the 97 articles published in foreign journals were scattered over 60 different journals.

Conclusion

The publication rate of abstracts presented at the 2008 and 2009 annual KARM meetings was 30.87% and the mean time to publication was 17.17±10.48 months.

Citations

Citations to this article as recorded by  
  • A Bibliometric Analysis Using Alternative Metrics for Articles in the Annals of Rehabilitation Medicine
    Seok Cheol Han, Hyo Jung Kang, Won Jae Lee, Hee Sup Chung, Jong Hyuk Lee
    Annals of Rehabilitation Medicine.2020; 44(2): 158.     CrossRef
  • Full publication of results initially presented in abstracts
    Roberta W Scherer, Joerg J Meerpohl, Nadine Pfeifer, Christine Schmucker, Guido Schwarzer, Erik von Elm
    Cochrane Database of Systematic Reviews.2018;[Epub]     CrossRef
  • 4,399 View
  • 49 Download
  • 2 Crossref
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