Citations

• Efficacy, Indications, and Safety of Intrathecal Baclofen Pump: A Narrative Review
  Alan D. Kaye, Se Yun Cheon, Morgan H. Roque, Caroline Gibbs, Karlee R. Mott, Alex M. Wandler, Syeda T. Munir, Junyu Lin, Shahab Ahmadzadeh, Harish Siddaiah, Sarah H. Myers, Kristin Nicole Bembenick, Sahar Shekoohi
  Current Pain and Headache Reports.2025;[Epub]     CrossRef
• Efficacy and Immunological Impact of Intrathecal Baclofen Pumps in Managing Spasticity in Multiple Sclerosis in Adult Patients: A Systematic Review
  Billy McBenedict, Wilhelmina Hauwanga, Anna Pogodina, Jeshua Nathaniel Devan, Kang Suen Goh, Ryan Chun Chien Yau, Berley Alphonse, Lorena Adolphsson, Bruno Lima Pessôa
  Sclerosis.2025; 3(1): 2.     CrossRef
• The Complex Role of Botulinum Toxin in Enhancing Goal Achievement for Post-Stroke Patients
  Miruna Ioana Săndulescu, Delia Cinteză, Daniela Poenaru, Claudia-Gabriela Potcovaru, Horia Păunescu, Oana Andreia Coman
  Toxins.2024; 16(4): 172.     CrossRef
• Intrathecal baclofen efficacy for managing motor function and spasticity severity in patients with cerebral palsy: a systematic review and meta-analysis
  Mahdi Masrour, Amir Zare, Ana Presedo, Mohammad Hossein Nabian
  BMC Neurology.2024;[Epub]     CrossRef
• Advances in Intrathecal Nanoparticle Delivery: Targeting the Blood–Cerebrospinal Fluid Barrier for Enhanced CNS Drug Delivery
  Ahmad Khalid Madadi, Moon-Jun Sohn
  Pharmaceuticals.2024; 17(8): 1070.     CrossRef
• Intrathecal Baclofen Infusion Pump for the Treatment of Painful Spastic Hemiplegia: A Case Report
  Juan J Medina-Pérez, Andrés Vega-Rosas, Rubén A Martínez-Espinosa, Daniel Chávez-González, Silvia G Coubert-Pelayo
  Cureus.2023;[Epub]     CrossRef

Spinal cord injury (SCI) has been recognized as a medically complex and life-disrupting condition. As the aging of the population accelerates, the trend of SCI has changed. This review aimed to provide comprehensive statistics and recent epidemiological changes in SCI and rehabilitation in Korea. All three insurance databases (National Health Insurance Service [NHIS], automobile insurance [AUI], and industrial accident compensation insurance [IACI]) were considered. These nationwide databases provide data on the current trends in term of incidence, etiology, and rehabilitation of SCI. Traumatic spinal cord injury (TSCI) was more frequent among the elderly in the NHIS compared to working age individuals in the AUI and IACI. In all three trauma-related insurance databases, male with TSCI outnumbered female. TSCI incidence per year was approximately 17 times higher among males than females, on average, in IACI. In all three insurances, the cervical level of TSCI was the most frequent. Although the ratio of SCI patients receiving rehabilitation treatment at primary and secondary hospitals increased for nine years, the increase in training on activities of daily living (ADL training) was found to be relatively small. This review provides a broader and comprehensive understanding of the incidence, etiology, and rehabilitation treatment of SCI in Korea.

Citations

• Effectiveness of a Community-Based Exercise Program for Ambulatory Individuals With Spinal Cord Injury: A Randomized Controlled Trial
  Sungchul Huh, Yuna Kim, Hyun-Yoon Ko, Mi Sook Yun, Yong Il Shin, Jung Lim Lee, Sung-Hwa Ko
  Archives of Physical Medicine and Rehabilitation.2025; 106(4): 481.     CrossRef
• Deep Learning-Based Prediction Model for Gait Recovery after a Spinal Cord Injury
  Hyun-Joon Yoo, Kwang-Sig Lee, Bummo Koo, Chan-Woo Yong, Chae-Won Kim
  Diagnostics.2024; 14(6): 579.     CrossRef
• Traumatic spinal cord injury: A four-year study in Puerto Rico
  Manuel F. Mas, Félix Pérez, Anna Blanco, Javier Deya, Natasha L. Frontera, Marcos R. Latimer, José Quintana, José G. Conde, Walter R. Frontera
  The Journal of Spinal Cord Medicine.2024; : 1.     CrossRef
• Risk of fracture among patients with spinal cord injury: A nationwide cohort study in South Korea
  Seonghye Kim, Bongseong Kim, Kyung-Do Han, Junhee Park, Jung Eun Yoo, Hea Lim Choi, Won Hyuk Chang, In Young Cho, Dong Wook Shin
  Bone.2024; 183: 117093.     CrossRef
• Significance of physical factors on activities of daily living in patients with tetraplegia after spinal cord injury: a retrospective study
  Kimin Yun, Jin-cheol Lim, Onyoo Kim
  BMC Sports Science, Medicine and Rehabilitation.2024;[Epub]     CrossRef
• Community-Based Exercise Programs Post Spinal Cord Injury Hospitalization: A Pilot Study for a Randomized, Multicenter, Double-Blind Controlled Setting
  Dongheon Kang, Jiyoung Park
  Life.2024; 14(9): 1135.     CrossRef
• Trends in the Incidence and Etiology of Non-Traumatic Spinal Cord Injury in Korea: A Nationwide Population-Based Study From 2007 to 2020
  Yoonjeong Choi, Ja-Ho Leigh, Jooeun Jeon, Goo Joo Lee, Hyung-Ik Shin, Moon Suk Bang
  Journal of Korean Medical Science.2023;[Epub]     CrossRef
• Risk Factors for Suicidality in Individuals With Spinal Cord Injury: A Focus on Physical and Functional Characteristics
  Sora Han, Wooyeung Kim, Onyoo Kim
  Annals of Rehabilitation Medicine.2023; 47(5): 377.     CrossRef

Objective
To systematically review the effect of intrathecal baclofen pump insertion in children with cerebral palsy (CP) with respect to scoliosis.
Methods
A systematic literature search was conducted in PubMed, Embase, Cochrane Library, and Google Scholar databases up to June 2022. The inclusion criteria were as follows: (1) studies with a quantitative study design; (2) studies with a study group of children with CP; (3) studies comparing scoliosis in children with and without an intrathecal baclofen pump; and (4) studies with Cobb’s angle as a parameter.
Results
Of the 183 studies found, four studies, all of which were retrospective comparative studies, met the aforementioned inclusion criteria. All studies were homogeneous (I2=0%, p=0.53) and intrathecal baclofen pump insertion accelerated the progression of scoliosis (standard mean difference=0.27; 95% confidence interval=0.07–0.48).
Conclusion
Intrathecal baclofen pumps have been used to alleviate spasticity in children with CP, thus aiding their daily activities and movements. However, their advantages and disadvantages should be reviewed after sufficient time considering the pumps’ negative effect on the course of scoliosis.

Citations

• From childhood to adulthood: Long-term assessment of continuous intrathecal baclofen therapy in non-ambulant spastic cerebral palsy
  B.H.M. Martens, M. Iskander, D.L. Soudant, G.F. Vles, L.A. Bonouvrié, O.P.M. Teernstra, J.S.H. Vles, R.J. Vermeulen
  European Journal of Paediatric Neurology.2025; 56: 17.     CrossRef
• Pre-op considerations in neuromuscular scoliosis deformity surgery: proceedings of the half day course at the 58th annual meeting of the Scoliosis Research Society
  Michelle C. Welborn, Gregory Redding, Patrick Evers, Lindsey Nicol, David F. Bauer, Rajiv R. Iyer, Selina Poon, Steven Hwang
  Spine Deformity.2024; 12(4): 867.     CrossRef
• Cervicothoracic ventral-dorsal rhizotomy for treatment of brachial hypertonia in cerebral palsy
  Sunny Abdelmageed, Mahalia Dalmage, James M. Mossner, Robin Trierweiler, Tim Krater, Jeffrey S. Raskin
  Child's Nervous System.2024; 40(9): 2835.     CrossRef
• Intrathecal Baclofen Therapy: Pros and Cons
  Sung-Rae Cho
  Annals of Rehabilitation Medicine.2023; 47(1): 1.     CrossRef

Objective
To examine the usefulness and feasibility of modified thread carpal tunnel release (TCTR) by comparing the results of using pre-existing commercial thread with those of a newly developed thread (Smartwire-01).
Methods
A total of 17 cadaveric wrists were used in the study. The modified TCTR method was practiced by two different experts. Pre-existing commercial surgical dissecting thread (Loop&Shear^TM) was used for five wrists and the newly developed Smartwire-01 was used for twelve wrists. The gross and microanatomy of the specimens were evaluated by a blinded anatomist.
Results
Both types of thread were able to cut the TCL similarly. Gross anatomy and histologic findings showed that there was no significant difference between the two types of threads. However, the practitioners felt that it was easier to cut the TCL using the newly-developed thread.
Conclusion
TCTR using Smartwire-01 was as effective as pre-existing Loop&Shear^TM, with better user experiences.

Citations

• Ultrasound-Guided Modified Thread Carpal Tunnel Release for Carpal Tunnel Syndrome: A Pilot Study
  Jaewon Kim, Jae Min Kim, Hae-Yeon Park, In Jong Kim
  Ultraschall in der Medizin - European Journal of Ultrasound.2025; 46(01): 57.     CrossRef
• Long-Term Outcomes of Ultrasound-Guided Thread Carpal Tunnel Release and Its Clinical Effectiveness in Severe Carpal Tunnel Syndrome: A Retrospective Cohort Study
  In Jong Kim, Jae Min Kim
  Journal of Clinical Medicine.2024; 13(1): 262.     CrossRef

Objective
To determine the efficacy of concentric vs. eccentric exercise in improving shoulder function, pain, and tendon characteristics for patients with rheumatoid arthritis and rotator cuff tendinopathy.
Methods
Forty patients with rheumatoid arthritis and rotator cuff tendinopathy were divided into either concentric or eccentric exercise groups, with 20 patients in each group. Patients received 12 sessions at a pace of 3 sessions per week. Shoulder Pain and Disability Index (SPADI), the visual analogue scale (VAS), supraspinatus and subscapularis thickness, echo pixels, and the Disease Activity Score-28-erythrocyte sedimentation rate (DAS-28-ESR) were assessed at baseline and post-treatment.
Results
There was a significant difference between the concentric and eccentric groups regarding SPADI and VAS scores in favor of the eccentric group. However, there was no significant difference between the two groups regarding tendon thickness, echo pixels, or DAS-28-ESR.
Conclusion
Eccentric exercises were more effective than concentric exercises in improving shoulder function and pain intensity. However, neither of the two types of exercises was superior in improving tendon characteristics or disease activity.

Citations

• Response: Eccentric Versus Concentric Exercises in Patients With Rheumatoid Arthritis and Rotator Cuff Tendinopathy: A Randomized Comparative Study (Ann Rehabil Med 2023;47:26-35)
  Mina Magdy Wahba, Mona Selim, Mohammed Moustafa Hegazy, Rasmia Elgohary, Mohammed Shawki Abdelsalam
  Annals of Rehabilitation Medicine.2024; 48(1): 3.     CrossRef
• Letter to the Editor: Eccentric Versus Concentric Exercises in Patients With Rheumatoid Arthritis and Rotator Cuff Tendinopathy: A Randomized Comparative Study
  Vanshika Agarwal, Jeyanthi. S, Adarsh Sharma
  Annals of Rehabilitation Medicine.2024; 48(1): 1.     CrossRef

Objective
To investigate the effect of 6 weeks of home-based boxing training on trunk performance, balance, fear of falling, and level of therapy enjoyment in individuals with chronic stroke.
Methods
Eighteen participants with chronic stroke were randomly divided into boxing and control groups (9 patients per group). The boxing group received home-based boxing training for 25 minutes plus balance and trunk exercise training for 15 minutes, while the control group received only home-based balance and trunk exercise training for 40 minutes, three days a week for 6 weeks. The Trunk Impairment Scale (TIS), Mini-Balance Evaluation Systems Test (Mini-BESTest), Activities-specific Balance Confidence (ABC) scale, and Physical Activity Enjoyment Scale (PACES) were assessed at baseline, and at 2, 4, and 6 weeks post-training. The Wilcoxon signed rank test and Mann–Whitney U-test were used to determine differences between pre- and post-training within and between groups. Statistical significance was set at p<0.05.
Results
The TIS scores significantly increased from 13 to 17 points in the boxing group (p<0.05) compared to an increase from 15 to 17 points in the control group (p<0.05). The Mini-BESTest scores significantly increased from 14 to 22 points in the boxing group (p<0.05) compared to an increase from 17 to 20 points in the control group (p<0.05). There were no differences in the TIS, Mini-BESTest, ABC, and PACES scores between the two groups.
Conclusion
Home-based boxing training with balance and trunk exercise training had a similar training effect compared to home-based balance and trunk exercise training.

Citations

• Therapeutic Intervention for Trunk Control Impairments in Central Nervous System Disorders: A Comprehensive Review of Methods and Efficacy
  Hiroaki Yamashita, Tatsuya Yamaoka, Ryota Shimomura, Sachimori Ichimura, Yuuki Murata, Akihiro Itoh, Tatsuya Mima, Satoko Koganemaru
  Progress in Rehabilitation Medicine.2025; 10: n/a.     CrossRef
• Effects of Taekwondo intervention on balance ability: A meta-analysis and systematic review
  Zhengfa Han, Hanyu Ju, Artur Kruszewski
  PLOS ONE.2025; 20(2): e0317844.     CrossRef
• Interactive Cognitive Motor Training: A Promising Approach for Sustainable Improvement of Balance in Older Adults
  Longhai Zhang, Jiawei Guo, Jing Zhang, Ling Zhang, Yanbing Li, Shutong Yang, Wenfei Zhu, Fei Guo
  Sustainability.2023; 15(18): 13407.     CrossRef

Objective
To evaluate the validity and reliability of the Thai version of the Freezing of Gait Questionnaire (FOG-Q) in individuals with Parkinson’s disease (PD).
Methods
The FOG-Q was translated into Thai according to the standard process. Fifty-six individuals with PD participated in the study. The content validity was assessed using the content validity index (CVI). The construct validity was evaluated by correlating Thai FOG-Q with Thai version of the Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) items 2.13 and 3.11, Thai version of the Falls Efficacy Scale-International (FES-I), Timed Up and Go test (TUG) and Berg Balance Scale (BBS) using Spearman’s correlation coefficient (rS). The correlation between Thai FOG-Q and clinical characteristics, for example, duration of PD and modified Hoehn and Yahr (mH&Y) stage was evaluated. Internal consistency and test-retest reliability were evaluated with Cronbach’s alpha (Cα) and intraclass correlation coefficient (ICC), respectively.
Results
The Thai FOG-Q had high content validity (CVI=0.96). The mean FOG-Q score was 9.0±4.9. The construct validity showed a strong positive correlation with MDS-UPDRS item 2.13 (rS=0.81), and moderate correlations with MDS-UPDRS item 3.11, FES-I, and TUG (rS=0.42–0.60). A negative correlation with BBS was found (rS=-0.32). It had a moderate correlation with mH&Y stage (rS=0.40). The Thai FOG-Q had good internal consistency (Cα=0.87) with excellent test-retest reliability (ICC=0.91).
Conclusion
The Thai FOG-Q has excellent validity and reliability. It is a useful instrument for the evaluation of FOG in individuals with PD.

Citations

• Validity, reliability, and measurement error of the Japanese version of the Freezing of Gait Questionnaire for patients with Parkinson’s disease
  Katsuya Sakai, Tsubasa Kawasaki, Hiroya Kiminarita, Kichol Kim, Jyunya Ogawa
  Physiotherapy Theory and Practice.2025; 41(4): 820.     CrossRef
• A Graph‐Theoretic Approach to Detection of Parkinsonian Freezing of Gait From Videos
  Qi Liu, Jie Bao, Xu Zhang, Chuan Shi, Catherine Liu, Rui Luo
  Statistics in Medicine.2025;[Epub]     CrossRef
• Psychometric properties of outcome measures for freezing of gait in Parkinson’s disease: a systematic review and meta-analysis
  Prisca Proietti, Ilaria Ruotolo, Alessandra Carlizza, Alessandro Ugolini, Giovanni Galeoto, Giovanni Fabbrini, Giovanni Sellitto
  Expert Review of Pharmacoeconomics & Outcomes Research.2025; : 1.     CrossRef
• The validation of a Japanese version of the New Freezing of Gait Questionnaire (NFOG-Q)
  Seira Taniguchi, Kohei Marumoto, Yuta Kajiyama, Gajanan Revankar, Michiko Inoue, Hiroshi Yamamoto, Rika Kayano, Eiji Mizuta, Ryuichi Takahashi, Emi Shirahata, Chizu Saeki, Tatsuhiko Ozono, Yasuyoshi Kimura, Kensuke Ikenaka, Hideki Mochizuki
  Neurological Sciences.2024; 45(7): 3147.     CrossRef
• A VO2peak prediction model in older adults' patients with Parkinson's disease
  Jaime Vásquez-Gómez, Armando Cifuentes-Amigo, Marcelo Castillo-Retamal, Antonio R. Zamunér
  Experimental Gerontology.2023; 181: 112285.     CrossRef

Objective
To assess the impact of a “one-stop”, multi-modal, hospital-associated-home-based prehabilitation model, helmed by a small core team, on newly diagnosed gastrointestinal and urological cancer patients planned for surgery.
Methods
This is a retrospective study in a tertiary public hospital, involving all newly diagnosed gastrointestinal and urological cancer patients planned for surgery. The primary outcome measure was the 6-minute walk test (6MWT). Other outcomes included physical, psychological and quality-of-life measures, and patient satisfaction surveys, taken at baseline, pre-operatively (post-prehabilitation), and at 3 months post-operatively.
Results
When comparing the baseline to pre-operatively (post-prehabilitation), there was a statistically significant improvement in the 6MWT (21.52 m, p<0.001), 30-Second Sit to Stand test (STS) (1.08 repetitions, p<0.001), Timed Up and Go test (TUG) (0.83 seconds, p=0.014) and Hospital Anxiety and Depression Scale (HADS) (total score 1.77, p<0.001). These were sustained (6MWT: 0.22, p=0.964; STS: 0.08 repetitions, p=0.863; TUG: 0.04 seconds, p=0.939) or further improved (HADS total score 2.06, p=0.003) at 3 months post-operatively. There was also a statistically significant improvement in the EuroQol-5 dimension health score (health-related quality-of-life measure) from baseline to 3 months post-operatively (7.04 points, p=0.001), with more than 90% overall patient satisfaction reported.
Conclusion
Prehabilitation applied via our model resulted in significant improvements in functional capacity, psychological and quality-of-life outcomes, sustained at 3 months post-operatively, and is a feasible and effective approach that is well-received by our patients.

Citations

• Feasibility, User Acceptance, and Outcomes of Using a Cancer Prehabilitation App for Exercise: Pilot Cohort Study
  Fuquan Zhang, Deepali Bang, Christine Alejandro Visperas, Mon Hnin Tun, San San Tay
  JMIR Formative Research.2025; 9: e64427.     CrossRef
• Measures of preoperative anxiety: Part two
  Katarzyna Nowicka-Sauer, Adam Zemła, Dorota Banaszkiewicz, Bartosz G. Trzeciak, Krzysztof Jarmoszewicz
  Anaesthesiology Intensive Therapy.2024; 56(1): 9.     CrossRef
• Prevention and treatment of noncognitive complications
  André van Zundert, Stephen P. Gatt, Tom Christophe van Zundert
  Saudi Journal of Anaesthesia.2023; 17(4): 557.     CrossRef

Objective
To explore the effects of tactile stimulation using air pressure at the auricular branch of the vagus nerve on autonomic activity in healthy individuals.
Methods
Three types of tactile stimulation were used in this study: continuous low-amplitude, continuous high-amplitude, and pulsed airflow. The tactile stimulations were provided to the cymba concha to investigate autonomic activity in 22 healthy participants. The mean heart rate (HR) and parameters of HR variability, including the standard deviation of R-R intervals (SDNN) and root mean square of successive R-R interval differences (RMSSD) were compared at baseline, stimulation, and recovery periods.
Results
Two-way repeated measures ANOVA indicated a significant main effect of time on HR (p=0.001), SDNN (p=0.003), and RMSSD (p<0.001). These parameters showed significant differences between baseline and stimulation periods and baseline and recovery periods in the post-hoc analyses. There were no significant differences in the changes induced by stimulation type and the interaction between time and stimulation type for all parameters. One-way repeated measures ANOVA showed that HR, SDNN, and RMSSD did not differ significantly among the three time periods during sham stimulation.
Conclusion
Parasympathetic activity can be enhanced by auricular tactile stimulation using air pressure, targeting the cymba concha. Further studies are warranted to investigate the optimal stimulation parameters for potential clinical significance.

Citations

• Stroking Stimuli to the Ear to Enhance Pleasant and Non-arousing Feelings while Listening to Sounds
  Yuta GOTO, Shogo OKAMOTO
  International Journal of Affective Engineering.2024; 23(3): 251.     CrossRef
• Relaxation Effects of Auricular Vibration Stimuli Synchronized with Music
  Yuta GOTO, Shogo OKAMOTO
  International Symposium on Affective Science and Engineering.2024; ISASE2024: 1.     CrossRef
• Effects of tactile auricular vagus nerve stimulation using heated and humidified airflow on cardiac autonomic activity: a pilot experimental study
  Soohyun Wi, Sungwoo Park, Byung-Mo Oh, Han Gil Seo, Yae Lim Lee, Woo Hyung Lee
  Clinical Autonomic Research.2024;[Epub]     CrossRef

Citations

• Validation of Wearable Digital Devices for Heart Rate Measurement During Exercise Test in Patients With Coronary Artery Disease
  Chul Kim, Jun Hyeong Song, Seung Hyoun Kim
  Annals of Rehabilitation Medicine.2023; 47(4): 261.     CrossRef