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Original Articles
Reliability and Validity of the Comprehensive Limb and Oral Apraxia Test: Standardization and Clinical Application in Korean Patients With Stroke
Sung-Bom Pyun, Yu Mi Hwang, Soo Yung Jo, Ji-Wan Ha
Ann Rehabil Med 2019;43(5):544-554.   Published online October 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.5.544
Objective
To develop and standardize the Limb and Oral Apraxia Test (LOAT) for Korean patients and investigate its reliability, validity, and clinical usefulness for patients with stroke.
Methods
We developed the LOAT according to a cognitive neuropsychological model of limb and oral praxis. The test included meaningless, intransitive, transitive, and oral praxis composed of 72 items (56 items on limb praxis and 16 items on oral praxis; maximum score 216). We standardized the LOAT in a nationwide sample of 324 healthy adults. Intra-rater and inter-rater reliability and concurrent validity tests were performed in patients with stroke. We prospectively applied the LOAT in 80 patients and analyzed the incidence of apraxia. We also compared the clinical characteristics between the apraxia and non-apraxia groups.
Results
The internal consistency was high (Cronbach’s alpha=0.952). The inter-rater and intra-rater reliability and concurrent validity were also high (r=0.924–0.992, 0.961–0.999, and 0.830, respectively; p<0.001). The mean total, limb, and oral scores were not significantly different according to age and education (p>0.05). Among the 80 patients with stroke, 19 (23.8%) had limb apraxia and 21 (26.3%) had oral apraxia. Left hemispheric lesions and aphasia were significantly more frequently observed in the limb/oral apraxia group than in the non-apraxia group (p<0.001).
Conclusion
The LOAT is a newly developed comprehensive test for limb and oral apraxia for Korean patients with stroke. It has high internal consistency, reliability, and validity and is a useful apraxia test for patients with stroke.

Citations

Citations to this article as recorded by  
  • Verbal and oral apraxia in patients with acute stroke: Frequency, relationship, and some risk factors
    Sarah Esmailzade Moghimi, Fatemeh Mohammadi, Fariba Yadegari, Mehdi Dehghan, Seyed Mohammad Masood Hojjati, Payam Saadat, Zahra Geraili, Maryam Alizadeh
    Applied Neuropsychology: Adult.2024; 31(2): 97.     CrossRef
  • The Effectiveness of Transcranial Magnetic Stimulation in Treating Apraxia
    Asma AlRuwaili, Rida Fatima, Amal Hussain, Mohammad Uzair, Turki Abualait, Kaleem Imdad, Shahid Bashir
    CNS & Neurological Disorders - Drug Targets.2024; 23(8): 1030.     CrossRef
  • Cerebrolysin Concentrate: Therapeutic Potential for Severe Oral Apraxia After Stroke: A Case Report
    Hyeonwoo Jeon, Doo Young Kim
    Brain & Neurorehabilitation.2024;[Epub]     CrossRef
  • Effect of Oral Apraxia on Dysphagia in Patients with Subacute Stroke
    Jei Hak Myung, Sung-Bom Pyun
    Dysphagia.2023; 38(1): 227.     CrossRef
  • Gerstmann Syndrome as a Disconnection Syndrome: A Single Case Diffusion Tensor Imaging Study
    Soo Hoon Yoon, Jae Ik Lee, Mun Jeong Kang, Hae In Lee, Sung-Bom Pyun
    Brain & Neurorehabilitation.2023;[Epub]     CrossRef
  • Culturally Competent Approaches for Neuropsychological Assessment for Differential Diagnosis of Dementia of Korean-Speaking Patients in the United States
    Michele K York, Stella H Kim, Dongwook D Lee, Victoria A Windham, Adriana M Strutt, Jennifer M Stinson, Stephen R McCauley
    Archives of Clinical Neuropsychology.2023; 38(3): 459.     CrossRef
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    Andrew Kertesz
    Aphasiology.2022; 36(1): 21.     CrossRef
  • The Incidence of Aphasia, Cognitive Deficits, Apraxia, Dysarthria, and Dysphagia in Acute Post Stroke Persian Speaking Adults
    Zahra Ghoreyshi, Reza Nilipour, Narges Bayat, Samaneh Sazegar Nejad, Masoud Mehrpour, Tabassom Azimi
    Indian Journal of Otolaryngology and Head & Neck Surgery.2022; 74(S3): 5685.     CrossRef
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  • 6 Web of Science
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Effect of Decreased Skeletal Muscle Index and Hand Grip Strength on Functional Recovery in Subacute Ambulatory Stroke Patients
Jin Gee Park, Kyeong Woo Lee, Sang Beom Kim, Jong Hwa Lee, Young Hwan Kim
Ann Rehabil Med 2019;43(5):535-543.   Published online October 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.5.535
Objective
To investigate the effect of decreased Skeletal Muscle Index (SMI) and hand grip strength on functional recovery in subacute ambulatory stroke patients.
Methods
Subacute stroke patients who were referred to the rehabilitation center were recruited. Decreased SMI and hand grip strength were diagnosed according to the Asian Working Group on Sarcopenia. Diagnostic criteria were decreased SMI and decreased unaffected hand grip strength. SMI was measured by bioelectrical impedance analysis. Unaffected hand grip strength was measured with a hand dynamometer. Patients were divided into two groups, decreased group (DG) and not-decreased group (NDG), according to the presence of decreased SMI and hand grip strength. Both groups received conventional stroke rehabilitation for 3 weeks. All patients were evaluated at the baseline and at 3 weeks after treatment. Functional status was evaluated with 4-meter walk test (4MWT), 6-minute walk test (6MWT), Timed Up and Go test (TUG), and Modified Barthel Index (MBI).
Results
Both groups showed improvement in 4MWT, TUG, and MBI. NDG showed improvement in 6MWT. Comparing improvements between the two groups, NDG showed more improvement in 6MWT and TUG than DG.
Conclusion
The presence of decreased SMI and hand grip strength had negative effects on functional recovery in subacute ambulatory stroke patients.

Citations

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    American Journal of Physical Medicine & Rehabilitation.2025; 104(2): 101.     CrossRef
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    Fatih Seğmen, Semih Aydemir, Temel Kayan, Firdevs Tuğba Bozkurt Biçer, Cihangir Doğu, Esra Yakışık Aktekin, Deniz Erdem, Elif Uzun Ata
    Medicina.2025; 61(2): 268.     CrossRef
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  • Hydroxytyrosol, a Promising Supplement in the Management of Human Stroke: An Exploratory Study
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    International Journal of Molecular Sciences.2024; 25(9): 4799.     CrossRef
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    Ageing Research Reviews.2024; 101: 102484.     CrossRef
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    So-Yeong Kim, Woon-Su Cho, Chi-Bok Park, Byeong-Geun Kim
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  • 8,062 View
  • 366 Download
  • 33 Web of Science
  • 35 Crossref
Effects of Breathing Exercises in Patients With Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis
Nutsupa Ubolnuar, Anong Tantisuwat, Premtip Thaveeratitham, Somrat Lertmaharit, Chathipat Kruapanich, Witaya Mathiyakom
Ann Rehabil Med 2019;43(4):509-523.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.509
Objective
To update evidence on the effects of breathing exercises (BEs) on ventilation, exercise capacity, dyspnea, and quality of life (QoL) in chronic obstructive pulmonary disease (COPD) patients.
Methods
Randomized controlled trials investigating the effects of BEs in COPD patients published through May 2018, were retrieved from five electronic databases (MEDLINE, CINAHL, Cochrane, Scopus, and ScienceDirect). Risk of bias and quality of evidence were assessed, using Cochrane Collaboration’s tool, and the Grading of Recommendation Assessment, Development, and Evaluation (GRADE) approach, respectively.
Results
Nineteen studies (n=745), were included. Quality of evidence, was low to moderate. When compared to the control groups, respiratory rate significantly (p≤0.001) improved in the pursed-lip breathing (PLB), ventilatory feedback (VF) plus exercise, diaphragmatic breathing exercise (DBE), and combined BEs. Additionally, PLB significantly improved tidal volume (p<0.001), inspiratory time (p=0.007), and total respiratory time (p<0.001). VF plus exercise significantly improved inspiratory capacity (p<0.001), and singing significantly improved the physical component of QoL, than did the control groups (p<0.001). All BEs did not significantly improve dyspnea, compared to the controls (p>0.05).
Conclusion
PLB, VF plus exercise, DBE, combined BEs, and singing could be used to improve ventilation and QoL. Based on low to moderate quality of evidence, use of these BEs to improve ventilation and QoL in COPD patients is conditional (Registration No. CRD42018102995).

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Effect of Sensory Impairment on Balance Performance and Lower Limb Muscle Strength in Older Adults With Type 2 Diabetes
Ratchanok Kraiwong, Mantana Vongsirinavarat, Vimonwan Hiengkaew, Petra von Heideken Wågert
Ann Rehabil Med 2019;43(4):497-508.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.497
Objective
To compare balance performance and lower limb muscle strength between older adults with type 2 diabetes mellitus (DM), with and without sensory impairments and non-DM groups. Influence of a number of sensory impairments, and muscle strength on balance performance were explored.
Methods
Ninety-two older adults with and without type 2 DM, were examined relative to visual function with the Snellen chart, Melbourne Edge test, and Howard-Dolman test, vestibular function with the modified Romberg test, proprioception of the big toe, and diabetic peripheral neuropathy with the Michigan Neuropathy Screening Instrument. Balance performances were evaluated with the Romberg test, Functional Reach Test (FRT), and Timed Up and Go test (TUG). Strength of knee and ankle muscles was measured.
Results
FRT of type 2 DM groups with at least two sensory impairments, was lower than the non-DM group (p<0.05). TUG of all DM groups, was worse than the non-DM group (p<0.01). Lower limb muscle strength of type 2 DM groups with two and three sensory impairments, was weaker than non-DM group (p<0.05). Regression analysis showed that type 2 DM with three sensory impairments, ankle dorsiflexors strength, and age were influential predictors of TUG.
Conclusion
There were significant differences, of muscle strength and balance performance among groups. Poorer balance and reduced lower limb strength were marked in older adults with type 2 DM, even ones without sensory impairment. Muscle weakness seemed to progress, from the distal part of lower limbs. A greater number of sensory impairments, weaker dorsiflexors, and advanced age influenced balance performance.

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Clinical Usefulness of the Korean Developmental Screening Test (K-DST) for Developmental Delays
Chul Hoon Jang, Seong Woo Kim, Ha Ra Jeon, Da Wa Jung, Han Eol Cho, Jiyong Kim, Jang Woo Lee
Ann Rehabil Med 2019;43(4):490-496.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.490
Objective
To evaluate the clinical usefulness of the Korean Developmental Screening Test (K-DST) via comparison with Korean Ages and Stages Questionnaire (K-ASQ) for the diagnosis of developmental delay in pediatric patients.
Methods
The K-DST and K-ASQ were used to screen pediatric patients who visited the hospital for evaluation and diagnosis of delayed development. Korean Bayley Scales of Infant Development-II (K-BSID-II) or Korean Wechsler Preschool and Primary Scale of Intelligence III (K-WPPSI-III) were used for the standardized assessment. Moreover, the final clinical diagnosis was confirmed by three expert physicians (rehabilitation doctor, psychiatrist, and neurologist). The sensitivity and specificity of each screening tool for the final diagnosis were investigated and correlated with standardized assessments.
Results
A total of 145 pediatric consultations were conducted, which included 123 developmental disorders (40 autism spectrum disorders, 46 global developmental delay/intellectual disability, and 37 developmental language disorders) and another 22 that were not associated with any such disorders. The sensitivity and specificity of K-DST based on the final clinical diagnosis were 82.9% and 90.9%, respectively, which were not significantly different from that of K-ASQ (83.7% and 77.3%). Both K-DST and K-ASQ showed good correlation with K-BSID-II and K-WPPSI-III. No significant difference was found between the K-DST and K-ASQ measures.
Conclusion
K-DST is an excellent screening tool and is expected to replace K-ASQ with high validity.

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    Sarah B. Mulkey
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    Saravanan Muthusamy, Deepika Wagh, Jason Tan, Max Bulsara, Shripada Rao
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    Seung-Han Shin, Ee-Kyung Kim, Seh-Hyun Kim, Hyun-Young Kim, Han-Suk Kim
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Correlations Between Values of Articulation Tests and Language Tests for Children With Articulation Disorder in Korea
Kwang Min Choi, Seung Don Yoo, Dong Hwan Kim, Jin Mann Chon, Seung Ah Lee, Young Rok Han, Myung Chul Yoo, Jae Joon Lee, Miryeong Yang, Young Hwa Choi, Min Ji Jung
Ann Rehabil Med 2019;43(4):483-489.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.483
Objective
To evaluate correlations between values of articulation tests and language tests for children with articulation disorder in Korea.
Methods
Data of outpatients with chief complaint of an articulation problem were retrospectively collected. Patients who underwent Urimal Test of Articulation and Phonation (U-TAP) with Assessment of Phonology and Articulation for Children (APAC), Preschool Receptive-Expressive Language Scale (PRES), or Receptive and Expressive Vocabulary Test (REVT) simultaneously were identified. Patients whose word-level percentages of correct consonants in U-TAP (UTAP_wC) were more than 2 standard deviations below the mean as diagnostic criteria for articulation disorder were selected. Those whose receptive language age (P_RLA), expressive language age (P_ELA), or combined language age (P_CLA) in PRES was delayed more than 24 months compared to their chronological age in months as diagnostic criteria for language disorder were excluded.
Results
Thirty-three children aged 3–6 years were enrolled retrospectively. PRES and U-TAP showed significant correlations for most of value relationships. PRES and APAC showed significant correlations for all value relationships except for receptive language age. All values of REVT were significantly correlated with all values from U-TAP, but not with any value from APAC. Articulation tests U-TAP and APAC showed significant correlations between percentages of correct consonants. Language tests PRES and REVT showed significant correlations for all value relationships.
Conclusion
This study suggests that articulation abilities and language abilities might be correlated in children with articulation disorder.

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The Effect of Simultaneous Antigravity Treadmill Training and Electrical Muscle Stimulation After Total Hip Arthroplasty: Short Follow-Up Time
Yukio Mikami, Naoya Orita, Takuma Yamasaki, Yoshiichiro Kamijo, Hiroaki Kimura, Nobuo Adachi
Ann Rehabil Med 2019;43(4):474-482.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.474
Objective
To assess the effectiveness of our devised hybrid physiotherapy regime using an anti-gravity treadmill and a low-frequency electrical stimulation device, as measured in patients with hip osteoarthritis after total hip arthroplasty (THA).
Methods
The outcomes of the postoperative rehabilitation in 44 patients who underwent THA for hip osteoarthritis were retrospectively examined. The conventional group (n=22) underwent the postoperative rehabilitation according to our protocol, while the hybrid group (n=22) underwent the same training, along with training on an anti-gravity treadmill and training using a low-frequency therapeutic device. The outcome measures were recorded and reviewed with the Numerical Rating Scale for pain, which rates pain on an 11-point scale from 0 to 10, surgical side knee joint extension force, 10-m walking test, Timed Up and Go test, and the 6-minute walking distance (6MD). The outcome measurement was taken 2 weeks after conducting pre-operation and antigravity treadmill training and electrical muscle stimulation, and compared the respective results.
Results
At the timeframe of 2 weeks from the surgery after conducting a devised hybrid physiotherapy, the values of knee extension muscle strength and 6MD were not worse in the hybrid group than conventional group. In the evaluation at 2 weeks after surgery, the knee extension muscle strength and 6MD values significantly decreased compared with the preoperative values only in the conventional group.
Conclusion
Lower limb muscular strength and endurance were maintained in the hybrid group, which suggested that hybrid physiotherapy could maintain physical functions early after THA operation.

Citations

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  • Functional assessment in patients undergoing total hip arthroplasty
    Richard J. Rivera, Theofilos Karasavvidis, Cale Pagan, Rowan Haffner, Michael P. Ast, Jonathan M. Vigdorchik, Eytan M. Debbi
    The Bone & Joint Journal.2024; 106-B(8): 764.     CrossRef
  • Sarcopenia and hip osteoarthritis: possible role for targeted electrical and biophysical muscle stimulation applications
    Ray Marks
    International Physical Medicine & Rehabilitation Journal.2023; 8(1): 80.     CrossRef
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  • 288 Download
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Effect of Pre-training and Post-training Nordic Exercise on Hamstring Injury Prevention, Recurrence, and Severity in Soccer Players
Ahmed Ebrahim Elerian, Mohsen M. El-Sayyad, Hend Adel Abdelhalim Dorgham
Ann Rehabil Med 2019;43(4):465-473.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.465
Objective
To investigate the effect of adding Nordic exercise as post-training in decreasing hamstring initial, recurrent injuries rates, and their severity.
Methods
In this randomly controlled trial study, 34 professional football players aged 21 to 35 years were randomly assigned into two groups (17 players each) from Sporting clubs at Alexandria, Egypt. For group one, Nordic hamstring exercise (NHE) was performed pre-training and post-training. For group two, NHE was only performed pre-training. The control group was the same team during the previous season. Length of the trial was 12 weeks. The Australian football association injury form was used to collect incidence of injuries for each subject in both groups.
Results
Pooled results based on total injuries showed that group one had significantly less hamstring initial injuries (92% less) than the previous season, while group two had 80% less initial injuries and 85% less recurrent injuries than previous season. Regarding the severity of injuries in term of mean number of absent days, it was 1 day for group one and 2.7 days for group two while it was 7.95 days for the previous season during total risk time of 116.3±13.2 and 117.6±5.7 exposure hours for group one and group two, respectively.
Conclusion
The use of NHE as a prevention protocol was effective in reducing all hamstring injuries with the use of NHE during pre-training and post-training having the greatest effect.

Citations

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  • Weekly Programming of Hamstring-Related Training Contents in European Professional Soccer
    Pedro Gómez-Piqueras, Antonio Martínez-Serrano, Tomás T. Freitas, Antonio Gómez Díaz, Irineu Loturco, Enric Giménez, Joao Brito, David García-López, Hernan Giuria, Paulino Granero-Gil, Shaun Huygaerts, Francesc Cos, Julio Calleja-González, Emmanuel Vallan
    Sports.2024; 12(3): 73.     CrossRef
  • Acute effects of Nordic hamstring exercise on hip and knee joints proprioception
    Mohsen Sadeghi, Mohammad H. Alizadeh, Hooman Minoonejad
    Journal of Bodywork and Movement Therapies.2024; 39: 382.     CrossRef
  • Comparison of the Effects of Pilates and Yoga Exercise on the Dynamic Balancing Ability and Functional Movement of Fencers
    So-Jung Lim, Hyun-Jin Kim, Yong-Soo Kim, Eunkuk Kim, Inyoung Hwang, Ju-Seop Kang
    Life.2024; 14(5): 635.     CrossRef
  • Implementing the Copenhagen Adductor Exercise and Nordic Hamstring Exercise in West African Academy Soccer Players: An Intervention Study
    Matthew D DeLang, Lasse Ishøi, Maren Nielsen Hole, Prince Wilson, Michael Segbefia, Kristian Thorborg
    International Journal of Sports Physical Therapy.2024;[Epub]     CrossRef
  • Comparing activity of the gluteus maximus and hamstring muscles in fatigue conditions between hamstring injury-experienced and inexperienced individuals
    Sirinda Jaotawipart, Hironobu Kuruma, Takuya Matsumoto, Shunsuke Tsutsumi, Hikari Takashina, Nene Iwamoto, Minjoon Kim
    Journal of Bodywork and Movement Therapies.2024; 40: 1693.     CrossRef
  • Effectiveness of different weekly frequencies of nordic hamstring exercise on performance and injury-associated factors in intermittent sports athletes: protocol of a randomised clinical trial
    Gianfranco Sganzerla, Rodrigo Luiz Carregaro, Paula Felippe Martinez, Silvio Assis de Oliveira-Junior
    European Journal of Physiotherapy.2023; 25(4): 223.     CrossRef
  • Effects of Different Hamstring Eccentric Exercise Programs on Preventing Lower Extremity Injuries: A Systematic Review and Meta-Analysis
    Chenxi Hu, Zhikun Du, Mei Tao, Yafeng Song
    International Journal of Environmental Research and Public Health.2023; 20(3): 2057.     CrossRef
  • Relationship Between Nordic Hamstring Strength and Single Leg Bridge Test in University Soccer Players
    Yuta Murakami, Satoru Nishida, Riku Yoshida, Kazuki Kasahara, Akira Kumazaki, Hirokazu Sakuma, Hirosi Fujimoto, Yuki Kaneko, Otoka Abe, Masatoshi Nakamura
    Journal of Sport Rehabilitation.2023; : 1.     CrossRef
  • Eccentric force and electromyogram comparison between the eccentric phase of the Nordic hamstring exercise and the razor hamstring curl
    Yuta Murakami, Satoru Nishida, Kaziki Kasahara, Riku Yoshida, Ryo Hayakawa, Masatoshi Nakamura, Esedullah Akaras
    PLOS ONE.2023; 18(12): e0293938.     CrossRef
  • Hamstring Strain Injury in Athletes
    Robroy L. Martin, Michael T. Cibulka, Lori A. Bolgla, Thomas A. Koc, Janice K. Loudon, Robert C. Manske, Leigh Weiss, John J. Christoforetti, Bryan C. Heiderscheit
    Journal of Orthopaedic & Sports Physical Therapy.2022; 52(3): CPG1.     CrossRef
  • Quo Vadis Nordic Hamstring Exercise-Related Research?—A Scoping Review Revealing the Need for Improved Methodology and Reporting
    Tobias Alt, Jannik Severin, Marcus Schmidt
    International Journal of Environmental Research and Public Health.2022; 19(18): 11225.     CrossRef
  • Efectividad de los ejercicios nórdicos sobre la incidencia de lesiones de isquiotibiales en futbolistas profesionales y amateur masculinos entre los 15 y 41 años. Revisión sistemática
    DM Tumiñá-Ospina, Y Rivas-Campo, PA García-Garro, A Gómez-Rodas, Diego Fernando Afanador
    Revista Iberoamericana de Ciencias de la Actividad Física y el Deporte.2022; 11(3): 47.     CrossRef
  • The Hamstrings: Anatomic and Physiologic Variations and Their Potential Relationships With Injury Risk
    José Afonso, Sílvia Rocha-Rodrigues, Filipe M. Clemente, Michele Aquino, Pantelis T. Nikolaidis, Hugo Sarmento, Alberto Fílter, Jesús Olivares-Jabalera, Rodrigo Ramirez-Campillo
    Frontiers in Physiology.2021;[Epub]     CrossRef
  • Hamstring Strain Injury (HSI) Prevention in Professional and Semi-Professional Football Teams: A Systematic Review and Meta-Analysis
    Carlo Biz, Pietro Nicoletti, Giovanni Baldin, Nicola Luigi Bragazzi, Alberto Crimì, Pietro Ruggieri
    International Journal of Environmental Research and Public Health.2021; 18(16): 8272.     CrossRef
  • Why methods matter in a meta-analysis: a reappraisal showed inconclusive injury preventive effect of Nordic hamstring exercise
    Franco M. Impellizzeri, Alan McCall, Maarten van Smeden
    Journal of Clinical Epidemiology.2021; 140: 111.     CrossRef
  • Exercise-Based Strategies to Prevent Muscle Injury in Elite Footballers: A Systematic Review and Best Evidence Synthesis
    Maurizio Fanchini, Ida Bo Steendahl, Franco M. Impellizzeri, Ricard Pruna, Gregory Dupont, Aaron J. Coutts, Tim Meyer, Alan McCall
    Sports Medicine.2020; 50(9): 1653.     CrossRef
  • No relationship between the nordic hamstring and two different isometric strength tests to assess hamstring muscle strength in professional soccer players
    Víctor Moreno-Pérez, Alberto Méndez-Villanueva, Aitor Soler, Juan Del Coso, Javier Courel-Ibáñez
    Physical Therapy in Sport.2020; 46: 97.     CrossRef
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Risk Assessment of Injury to Palmar Cutaneous Branch of the Median Nerve Using High-Resolution Ultrasound
Young Ha Jeong, Jun Ho Choi, Hyuk Sung Choi, Seok Kang, Seung Nam Yang, Joon Shik Yoon
Ann Rehabil Med 2019;43(4):458-464.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.458
Objective
To evaluate the relationship between the palmar cutaneous branch of median nerve (PCBMN) and surrounding anatomical structures by using high-resolution ultrasound (HRUS) to assess the risk of PCBMN injury.
Methods
The PCBMN course and the characteristics of bilateral distal forearms and wrists of 30 healthy volunteers were identified. The distance between PCBMN and other anatomical structures at three different levels along its course were measured using HRUS. Moreover, the depth of PCBMN from skin and its cross-sectional area (CSA) were measured.
Results
HRUS showed the PCBMN in all subjects. PCBMN branched off from the radial aspect of the median nerve (MN) at 4.69±0.89 cm proximal to the bistyloid line (BSL) and extended radially toward the flexor carpi radialis (FCR) tendon. PCBMN was within the ulnar edge of FCR tendon sheath, and became more superficial and perforated the antebrachial fascia between the FCR tendon laterally and the palmaris longus (PL) tendon medially. PCBMN was located at 4.08±0.72 mm on the ulnar aspect of the FCR tendon and 4.78±0.36 mm radially on the PL tendon at BSL. At the distal wrist crease level, the PCBMN was located at 5.68±0.58 mm on the ulnar side of the FCR tendon. The PCBMN depth from skin at BSL and its branching point was 1.92±0.41 and 7.95±0.79 mm, respectively. The PCBMN CSA was 0.26±0.15 mm2 at BSL.
Conclusion
HRUS can be used to identify PCBMN and its relationship with other anatomical structures. Our data can be used to predict PCBMN location, and prevent complications associated with invasive procedures involving the wrist.

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    Annora Ai-Wei Kumar, Matthew Lawson-Smith
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    Jiawen Wu, Jinyan Xu, Qingyuan Yu, Cheng Chen, Yu Xiao, Junmin Bao, Liangxi Yuan
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    Hae-Yeon Park, Jae Min Kim, In Jong Kim, Minsuk Kang, Jung Ryul Ham, Yong Seok Nam
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    Wei-Ting Wu, Ke-Vin Chang, Yu-Chun Hsu, Yuan-Yuan Tsai, Kamal Mezian, Vincenzo Ricci, Levent Özçakar
    Diagnostics.2023; 13(11): 1928.     CrossRef
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    Tarik Mujadzic, Harold I. Friedman, Mirza M. Mujadzic, Charles Gober, Elliot Chen, Abdelaziz Atwez, Martin Durkin, Mirsad M. Mujadzic
    Annals of Plastic Surgery.2021; 86(6S): S503.     CrossRef
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    Sarah Henning, Matthew Weston, Michael David
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    Travis J. Miller, Christopher V. Lavin, Arash Momeni, Derrick C. Wan
    Surgical Clinics of North America.2021; 101(5): 813.     CrossRef
  • Is Palmar Cutaneous Branch of the Median Nerve More Swollen in Carpal Tunnel Syndrome?
    Ha Mok Jeong, Young Ha Jeong, Joon Shik Yoon
    Annals of Rehabilitation Medicine.2021; 45(4): 325.     CrossRef
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    Áurea V. R. Mohana Borges, Sergio A. L Souza
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    Stefano Bianchi, Douglas F. Hoffman, Giorgio Tamborrini, Pierre‐Alexandre Poletti
    Journal of Ultrasound in Medicine.2020; 39(12): 2469.     CrossRef
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Effects of Combined Upper Limb Robotic Therapy in Patients With Tetraplegic Spinal Cord Injury
Joo Hwan Jung, Hye Jin Lee, Duk Youn Cho, Jung-Eun Lim, Bum Suk Lee, Seung Hyun Kwon, Hae Young Kim, Su Jeong Lee
Ann Rehabil Med 2019;43(4):445-457.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.445
Objective
To confirm the effects of combined upper limb robotic therapy (RT) as compared to conventional occupational therapy (OT) in tetraplegic spinal cord injury (SCI) patients and to suggest the optimized treatment guidelines of combined upper limb RT.
Methods
After subject recruitment and screening for eligibility, the baseline evaluation for outcome measures were performed. We evaluated the Graded and Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP), the American Spinal Injury Association upper extremity motor score, grip and pinch strength, and the Spinal Cord Independence Measurement III (SCIM-III). In this study, the pre-tested participants were divided randomly into the RT and OT group. The utilized interventions included combined upper limb RT using ArmeoPower and Amadeo (RT group), or conventional OT (OT group) in addition to daily inpatient rehabilitation program. The participants underwent 40 minutes×3 sessions×5 weeks of interventions.
Results
A total of 30 tetraplegic SCI patients completed entire study program. After 5 weeks of intervention, both groups demonstrated increases in GRASSP-strength and SCIM-III. The manual muscle test scores of elbow flexion, elbow extension, 2-5th metacarpophalangeal extension, and SCIM-III subscores of bathing-upper, dressing-upper, and grooming as well as the GRASSP-qualitative prehension score were noted to have been significantly increased in the RT group as evaluated. The OT group showed improvements in the GRASSP-quantitative prehension score and some items in grip and pinch strength. There was no significant difference between the two groups in almost all measurements except for the SCIM-III bathing-upper subscore.
Conclusion
Combined upper limb RT demonstrated beneficial effects on the upper limb motor function in patients with tetraplegic SCI, which were comparable with conventional OT.

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  • Anxiety and Depression in Pediatric-Onset Traumatic Spinal Cord Injury: A Systematic Review
    Mohammad Mofatteh, Mohammad Sadegh Mashayekhi, Saman Arfaie, Yimin Chen, Armaan K. Malhotra, Georgios P. Skandalakis, Mohammed Ali Alvi, Fardad T. Afshari, Shakila Meshkat, Famu Lin, Ebtesam Abdulla, Ayush Anand, Xuxing Liao, Roger S. McIntyre, Carlo Sant
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  • Technology-Assisted Upper Limb Therapy (TAULT): Evaluation of Clinical Practice at a Specialised Centre for Spinal Cord Injury in Switzerland
    Daniela B. Kuchen, Beatrice Hubacher, Andris Ladner, Inge-Marie Velstra, Mario Widmer
    Healthcare.2023; 11(23): 3055.     CrossRef
  • Reliability Validity and Responsiveness of the Spinal Cord Independence Measure 4th Version in a Multicultural Setup
    Amiram Catz, Malka Itzkovich, Keren Elkayam, Dianne Michaeli, Ilana Gelernter, Yoav Benjamini, Harvinder Singh Chhabra, Luigi Tesio, Einat Engel-Haber, Emiliana Bizzarini, Claudio Pilati, Giulio Del Popolo, Ilaria Baroncini, Nan Liu, Paulo Margalho, Thaba
    Archives of Physical Medicine and Rehabilitation.2022; 103(3): 430.     CrossRef
  • Donor activation focused rehabilitation approach to hand closing nerve transfer surgery in individuals with cervical level spinal cord injury
    Lorna C. Kahn, Adam G. Evans, Elspeth J. R. Hill, Ida K. Fox
    Spinal Cord Series and Cases.2022;[Epub]     CrossRef
  • The Impact of Robotic Therapy on the Self-Perception of Upper Limb Function in Cervical Spinal Cord Injury: A Pilot Randomized Controlled Trial
    V. Lozano-Berrio, M. Alcobendas-Maestro, B. Polonio-López, A. Gil-Agudo, A. de la Peña-González, A. de los Reyes-Guzmán
    International Journal of Environmental Research and Public Health.2022; 19(10): 6321.     CrossRef
  • The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications
    Carmen Delia Nistor-Cseppento, Anamaria Gherle, Nicoleta Negrut, Simona Gabriela Bungau, Anca Maria Sabau, Andrei-Flavius Radu, Alexa Florina Bungau, Delia Mirela Tit, Bogdan Uivaraseanu, Timea Claudia Ghitea, Diana Uivarosan
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    Tao Zhang, Kang Li, Zi-Lu Zhang, Kai Gao, Chao-Liang Lv
    Neural Regeneration Research.2021; 16(4): 772.     CrossRef
  • Do any physiotherapy interventions increase spinal cord independence measure or functional independence measure scores in people with spinal cord injuries? A systematic review
    Lisa A. Harvey, Joanne V. Glinsky, Jackie Chu
    Spinal Cord.2021; 59(7): 705.     CrossRef
  • Design and Performance Evaluation of a Hybrid Hand Exoskeleton for Hand Opening/Closing
    Muhammad Ahsan Gull, Shaoping Bai, Jakob Udby Blicher, Tobias Glaston Staermose
    Journal of Medical Devices.2021;[Epub]     CrossRef
  • Upper Limb Robotic Rehabilitation for Patients with Cervical Spinal Cord Injury: A Comprehensive Review
    Giovanni Morone, Alessandro de Sire, Alex Martino Cinnera, Matteo Paci, Luca Perrero, Marco Invernizzi, Lorenzo Lippi, Michela Agostini, Irene Aprile, Emanuela Casanova, Dario Marino, Giuseppe La Rosa, Federica Bressi, Silvia Sterzi, Daniele Giansanti, Al
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    Izhar Ahmad, Tanzeel Ahmad, Mohd Aleemuddin Quamri
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The Value of MicroRNAs as an Indicator of the Severity and the Acute Phase of Spinal Cord Injury
Junyoung Park, Dongsoo Yi, Jiyoon Jang, Jiseon Hong
Ann Rehabil Med 2019;43(3):328-334.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.328
Objective
To assess the role of miRNA-21 and miRNA-223 in a balloon-compression model of spinal cord injury (SCI).
Methods
A total of 50 male Wistar rats (n=50) were divided into the three groups: the group A (n=15, insertion of the unflated Fogarty balloon catheter), the group B (n=15, insertion of the Fogarty balloon catheter at a volume of 20 μL) and the group C (n=15, insertion of the Fogarty balloon catheter at a volume of 50 μL). After the behavioral test, RNA isolation, microRNA expression profiling using microarrays and quantitative polymerase chain reaction, measurements were compared between the three groups.
Results
Despite a lack of significant differences in time-dependent changes in miRNA-21 expression levels between the three groups at 4 hours, there were significant differences in them at 1, 3, and 7 days (p<0.05). Moreover, there were significant differences in time-dependent changes in miRNA-223 expression levels between the three groups at 4 hours and 1, 3, and 7 days (p<0.05). Furthermore, miRNA-223 expression levels reached the highest at 1 day but were decreased with time thereafter in all the three groups.
Conclusion
Expression levels of miRNA-21 and miRNA-223 might be associated with the severity and acute phase of SCI, respectively. It is mandatory, however, to analyze changes in levels of inflammatory markers and the relevant biological pathways.

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  • Spinal Cord Injury: From MicroRNAs to Exosomal MicroRNAs
    Xiangyang Xu, Ruyin Liu, Yunpeng Li, Cheng Zhang, Chuanghao Guo, Jiong Zhu, Jiaan Dong, Liyun Ouyang, Mohammad Reza Momeni
    Molecular Neurobiology.2024; 61(8): 5974.     CrossRef
  • Long non-coding RNA-small nucleolar RNA host gene 7 regulates inflammatory responses following spinal cord injury by regulating the microRNA-449a/TNF-α-induced protein 3-interacting protein 2 axis
    Chunlei He, Jianhua Xiao, Yongjun Ye, Shiqiao Huang, Yanchun Zhong, Lulin Liu, Wuyang Liu, Sheng Liu
    Bioengineered.2022; 13(4): 10215.     CrossRef
  • Improving Diagnostic Workup Following Traumatic Spinal Cord Injury: Advances in Biomarkers
    Simon Schading, Tim M. Emmenegger, Patrick Freund
    Current Neurology and Neuroscience Reports.2021;[Epub]     CrossRef
  • Serum exosomal microRNA transcriptome profiling in subacute spinal cord injured rats
    Shu-Qin Ding, Yu-Qing Chen, Jing Chen, Sai-Nan Wang, Fei-Xiang Duan, Yu-Jiao Shi, Jian-Guo Hu, He-Zuo Lü
    Genomics.2020; 112(2): 2092.     CrossRef
  • Serum exosomal microRNA transcriptome profiling in subacute spinal cord injured rats
    Shu-Qin Ding, Yu-Qing Chen, Jing Chen, Sai-Nan Wang, Fei-Xiang Duan, Yu-Jiao Shi, Jian-Guo Hu, He-Zuo Lü
    Genomics.2020; 112(6): 5086.     CrossRef
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  • 107 Download
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Quality of Life Associated Factors in a North African Sample of Lower Limbs Amputees
Houda Migaou, Amine Kalai, Yafa Haj Hassine, Anis Jellad, Soumaya Boudokhane, Zohra Ben Salah Frih
Ann Rehabil Med 2019;43(3):321-327.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.321
Objective
To study factors associated to the quality of life in a North African sample of lower limbs amputees.
Methods
We conducted a prospective study in the Department Physical Medicine and Rehabilitation, University Hospital of Monastit, Tunisia. A consecutive sample of patients with amputations of the lower limbs was included. The evaluated parameters were quality of life using the Short-Form quality-of-life questionnaire (SF-36), pain using a visual analog scale, function using, the perimeter of walking (PW), the Special Interest Group of the Amputee Medicine (SIGAM) and the Locomotion Capacities Index of the Prosthetic Profile of the Amputee (LCI), and psychological status thanks to the Hospital Anxiety and Depression scale. In the study, the patients were evaluated at the first consultation (T0) and again at 12 months (T1).
Results
We included 85 patients (age, 59.3±16.7 years) with a sex ratio of 3. The patient quality of life was positively correlated to distal type of amputation, traumatic origin, better LCI (p≤0.001, r=0.349), SIGAM (p=0.046) and PW. A negative correlation was noted with age (p=0.012, r=-0.483) and higher psychological scores (p=0.002, r=-0.321).
Conclusion
In our sample of North African lower limbs amputees the age and the functional status were the most important predictors of the quality of life.

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    Doriane Pelzer, Charlotte Beaudart, Aurore Thibaut, Stephen Bornheim, Jean-François Kaux
    Prosthetics & Orthotics International.2025; 49(1): 14.     CrossRef
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    Journal of Bodywork and Movement Therapies.2025; 41: 115.     CrossRef
  • How To Improve Patient Selection in Individuals With Lower Extremity Amputation Using a Bone-anchored Prosthesis
    Charlotte van Vliet-Bockting, Robin Atallah, Jan Paul M. Frölke, Ruud A. Leijendekkers
    Clinical Orthopaedics & Related Research.2025;[Epub]     CrossRef
  • Anxiety and Depressive Symptoms in Moroccan Patients Following Major Lower Limb Amputation: A Three-Month Follow-Up
    Mohammed Elaatmani, Aziz Ahizoune, Amine El Maqrout, Mohamed Kharmaz, Radouane Abouqal, Khalid Abidi
    Cureus.2024;[Epub]     CrossRef
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    Bibek Banskota, Rajan Bhusal, Niraj Bhattarai, Yam Prakash Gurung, Prakash Kumar Yadav, Ashok Kumar Banskota
    BMC Sports Science, Medicine and Rehabilitation.2024;[Epub]     CrossRef
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    Syeda Zainab Fatima
    Wiener Medizinische Wochenschrift.2023; 173(13-14): 329.     CrossRef
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    JPO Journal of Prosthetics and Orthotics.2023; 35(1): e30.     CrossRef
  • What Is Hidden behind Amputation? Quanti-Qualitative Systematic Review on Psychological Adjustment and Quality of Life in Lower Limb Amputees for Non-Traumatic Reasons
    Laura Calabrese, Marina Maffoni, Valeria Torlaschi, Antonia Pierobon
    Healthcare.2023; 11(11): 1661.     CrossRef
  • Quantifying Step Count and Oxygen Consumption with Portable Technology during the 2-Min Walk Test in People with Lower Limb Amputation
    John D. Smith, Gary Guerra
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  • Quality of Life and Associated Factors Among Male Wheelchair Handball Athletes
    David dos Santos Calheiros, Jorge Lopes Cavalcante Neto, Flávio Anderson Pedrosa de Melo, Fábio Ítalo Pedrosa de Melo, Mey de Abreu van Munster
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    EClinicalMedicine.2021; 35: 100874.     CrossRef
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    Victor Hugo De Melo, Ricardo Augusto Leoni de Sousa, Alex Cleber Improta-Caria, Marco Antônio Prado Nunes
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    Michael P. Dillon, Matthew Quigley, Phil Stevens, Yuri Balasanov, Sarah P. Anderson
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Single Dose Therapy of Zoledronic Acid for the Treatment of Transient Osteoporosis of Hip
Sanjay Agarwala, Mayank Vijayvargiya
Ann Rehabil Med 2019;43(3):314-320.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.314
Objective
To shorten the natural course of transient osteoporosis of hip (TOH), which is a self-limiting idiopathic condition and requires 6–12 months for the resolution of symptoms, various therapies including treatment with bisphosphonates have been attempted. There exist fewer case reports evaluating the effect of bisphosphonates in TOH and most of them lack radiographic evidence of resolution of disease. The present study was carried out with an aim to evaluate the clinical and radiological outcomes of TOH patients subsequent to treatment with a single dose of zoledronic acid.
Methods
Data of 19 adult male and non-pregnant female patients with TOH treated with zoledronic acid were included in the study. Efficacy was assessed using changes in clinical signs and symptoms, visual analogue scale pain score, and changes in bone marrow edema (BME) in magnetic resonance imaging (MRI).
Results
Mean age of the patients was 42.1 years, 17 being males. The mean time of onset of symptom was 4 weeks. Subsequent to treatment, the patients were pain-free and had no limp within an average of 2.8 weeks (range, 2–5 weeks) and remained asymptomatic at a mean follow-up of 35 months (range, 6–54 months). The post-treatment MRI showed resolution of BME in approximately 84% (16/19) of patients at 3 months. No major adverse events were reported. None of the patients progressed to avascular necrosis at their last follow-up.
Conclusion
Intravenous single dose administration of zoledronic acid provides early pain relief and complete reversal of TOH. Consequently, zoledronic acid is proposed as a new paradigm in the management of TOH.

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Effectiveness of Active Rehabilitation Program on Sports Hernia: Randomized Control Trial
Walid Ahmed Abouelnaga, Nancy Hassan Aboelnour
Ann Rehabil Med 2019;43(3):305-313.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.305
Objective
To determine whether an active rehabilitation program that involves repetitive effortful muscle contractions, including core stability, balancing exercises, progressive resistance exercises, and running activities, after a sports hernia, is effective.
Methods
Forty soccer players with sports hernias were randomly divided into two equal groups: group A (active rehabilitation program) and group B (conventional treatment). The methods of assessment included a visual analog scale (VAS) and hip internal and external range of motion assessments. Group A received conventional treatment (heat, massage, transcutaneous electrical nerve stimulation, and mobilization) plus an active rehabilitation program, while group B received only conventional treatment. Three treatment sessions were given each week for 2 months. Evaluations were performed pre- and post-treatment.
Results
A decrease in VAS was seen in both groups at the end of treatment, 80.25% in group A and 41.93% in group B. The difference between the two groups was statistically significant (p=0.0001), whereas there were no statistical differences in internal and external rotation between the groups at the end of treatment (p>0.05). After treatment, an improvement in outcome measures of group A compared to group B (p=0.01) was seen. Thirteen patients in group A and only three patients in group B returned to sports activities without groin pain.
Conclusion
Active rehabilitation was effective for sports hernia management measured by a decrease in pain and the return to sports.

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  • Does Core Training Improve Agility Performance in Soccer Players With Groin Pain? A Randomized, Single-Blind Study
    Fatma Chaari, Abderrahmane Rahmani, Nicolas Peyrot, Mohamed A. Harrabi, Thouraya Fendri, Haithem Rebai, Sébastien Boyas, Sonia Sahli
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Comparison of Obesity Related Index and Exercise Capacity Between Center-Based and Home-Based Cardiac Rehabilitation Programs
Hyeng-Kyu Park, Ki-Hong Kim, Ji-Hyun Kim, Min-Keun Song, In-Sung Choi, Jae-Young Han
Ann Rehabil Med 2019;43(3):297-304.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.297
Objective
To compare a center-based cardiac rehabilitation (CR) program with a home-based CR program in terms of improving obesity related index and cardiopulmonary exercise capacity after the completing a phase II CR program.
Methods
In this study, there were seventy-four patients with acute myocardial infarction after percutaneous coronary intervention who were analyzed. Patients with mild to moderate risk (ejection fraction >40%) were included in the group. The patients underwent an exercise tolerance test by measurement of the modified Bruce protocol at three assessment points. Those in the center-based CR group participated in a 4-week training program with electrocardiography monitoring of the patient’s progress and results, while those patients who were in the home-based CR group underwent self-exercise training. We measured the obesity related indices such as body mass index, fat free mass index (FFMI), and cardiopulmonary exercise capacity including peak oxygen consumption (VO2max), metabolic equivalents (METs), heart rate, resting systolic blood pressure and the diastolic blood pressure of the participants and noted the results.
Results
Of the 74 patients, 25 and 49 participated in the center-based and home-based CR programs, respectively. Both groups showed significant improvement in VO2max and METs at 1-month and 6-month follow-up. However, FFMI was significantly improved only in the center-based CR group after 1 month of the phase II CR.
Conclusion
Both groups identified in the study showed significant improvement of VO2max and METs at 1-month and 6-month follow-up. However, there was no significant difference in the intergroup analysis. A significant improvement of FFMI was seen only in the center-based CR group after phase II CR.

Citations

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  • A scale for measuring home-based cardiac rehabilitation exercise adherence: a development and validation study
    Zhen Yang, Yuanhui Sun, Huan Wang, Chunqi Zhang, Aiping Wang
    BMC Nursing.2023;[Epub]     CrossRef
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    Qiaowei Li, Fang Wang, Xiaoqun Liu, Huijuan Zhong, Feng Huang, Pengli Zhu
    Archives of Physical Medicine and Rehabilitation.2022; 103(8): 1663.     CrossRef
  • Do Patients Maintain Proper Long-Term Cardiopulmonary Fitness Levels After Cardiac Rehabilitation? A Retrospective Study Using Medical Records
    Chul Kim, Hee Eun Choi, Jin Hyuk Jang, Jun Hyeong Song, Byung-Ok Kim
    Annals of Rehabilitation Medicine.2021; 45(2): 150.     CrossRef
  • An observational study substantiating the statistical significance of cardiopulmonary exercise with laboratory tests during the acute and subacute phases of center and home-based cardiac rehabilitation
    Jeong Jae Lee, Jun Young Ko, Seungbok Lee
    Medicine.2021; 100(31): e26861.     CrossRef
  • Rehabilitación cardíaca fase 2 post infarto agudo al miocardio.
    Kirby Gutiérrez Arce, Jessy Estefanía Funez Estrada, Cristian Yovany Rojas Aboyte, Perla Lizeth Hernández Cortés Hernández Cortés, María Cristina Enríquez Reyna
    Revista de Ciencias del Ejercicio FOD.2021;[Epub]     CrossRef
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The Role of Regular Physical Therapy on Spasticity in Children With Cerebral Palsy
Heewon Lee, Eun Kyung Kim, Dong Baek Son, Youngdeok Hwang, Joon-Sung Kim, Seong Hoon Lim, Bomi Sul, Bo Young Hong
Ann Rehabil Med 2019;43(3):289-296.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.289
Objective
To investigate the effect of physical therapy (PT) intervention on spasticity in patients with cerebral palsy (CP), and to assess the degree of deterioration of spasticity when regular PT is interrupted in those patients.
Methods
We recruited 35 children with spastic CP who visited our hospital for PT, and whose Modified Tardieu Scale (MTS) scores were serially recorded including before and after a 10-day public holiday time frame period. The outcome measures were the angle of range of motion (ROM) of dorsiflexion of the ankle joint (R1 and R2) in the knee flexion and extension positions as assessed using the MTS.
Results
The range of dorsiflexion of the ankle joint (R1 and R2) after the holiday period was significantly decreased as compared with that measured ROM noted before the holiday period, regardless of the knee position, age, or gross motor function. The dynamic component of the MTS (R2–R1) showed a slight decrease in the knee flexion position.
Conclusion
Interruption of regular PT aggravated spasticity and decreased ankle joint ROM in children with spastic CP. Our findings suggest that regular PT in the care continuum for children with CP is crucial for the maintenance of ROM in the spastic ankle joints.

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    Amira F. El-Sheikh, Alaa B. Hassan, Nanees E. Mohamed
    Journal of Taibah University Medical Sciences.2025; 20(1): 73.     CrossRef
  • F‐words and early intervention ingredients for non‐ambulant children with cerebral palsy: A scoping review
    Ana Carolina De Campos, Álvaro Hidalgo‐Robles, Egmar Longo, Claire Shrader, Ginny Paleg
    Developmental Medicine & Child Neurology.2024; 66(1): 41.     CrossRef
  • F‐words e ingredientes de las intervenciones tempranas dirigidas a niños no ambulantes con parálisis cerebral: Una revisión exploratoria
    Ana Carolina de Campos, Álvaro Hidalgo‐Robles, Egmar Longo, Claire Shrader, Ginny Paleg
    Developmental Medicine & Child Neurology.2024;[Epub]     CrossRef
  • F‐words e ingredientes das intervenções precoces para crianças com paralisia cerebral não deambuladoras: uma revisão de escopo
    Ana Carolina De Campos, Álvaro Hidalgo‐Robles, Egmar Longo, Claire Shrader, Ginny Paleg
    Developmental Medicine & Child Neurology.2024;[Epub]     CrossRef
  • F‐Wörter und Interventionsinhalte in der Frühförderung nicht gehfähiger Kinder mit Cerebralparese: eine umfangreiche Literaturübersicht
    Ana Carolina De Campos, Álvaro Hidalgo‐Robles, Egmar Longo, Claire Shrader, Ginny Paleg
    Developmental Medicine & Child Neurology.2024;[Epub]     CrossRef
  • INVESTIGATION OF THE EFFECT OF A PHYSIOTHERAPY AND REHABILITATION PROGRAM IN A CASE WITH CONGENITAL CENTRAL HYPOVENTILATION SYNDROME AND CEREBRAL PALSY: A CASE REPORT
    Mustafa Burak, Sinem Erturan, Bülent Elbasan
    Sağlık Bilimleri Dergisi.2024; 33(1): 154.     CrossRef
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    Hisham M. Hussein, Monira I. Aldhahi, Hand Zamel M. Alshammari, Salma Khamis S. Alshammari, Sarah Naif M. Alrashidi, Shahad Lafi M. Alreshidi, Mazin M. Al Ayasrah, Amsha Alhumaidi Alshammari, Khulood Khleiwi R. Altamimi, Ahmed M. Gabr, Abdulaziz Mohammed
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    Hisham M. Hussein, Monira I. Aldhahi, Ahmed Abdelmoniem Ibrahim
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    Włodzisław Kuliński, Emilia Gryl
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    Włodzisław Kuliński, Magdalena Żukowska
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  • Impact on rehabilitation programs during COVID-19 containment for children with pediatric and perinatal stroke
    Marta Bertamino, Sara Cornaglia, Alice Zanetti, Alessia Di Rocco, Anna Ronchetti, Sara Signa, Mariasavina Severino, Paolo Moretti
    European Journal of Physical and Rehabilitation Medicine.2020;[Epub]     CrossRef
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Objective
To investigate if therapeutic horseback riding (THR) can improve language and cognitive function in children with autism spectrum disorder (ASD) or intellectual disability (ID).
Methods
We conducted a prospective case-control study on children diagnosed with ASD or ID. Eighteen and 11 children were enrolled for THR and control groups, respectively. For 8 weeks, those in the THR group underwent conventional therapy plus 30 minutes of THR per week while controls only received conventional therapy. Participants’ language (using Receptive and Expressive Vocabulary Test [REVT] and Preschool Receptive-Expressive Language Scale [PRES]) and cognitive abilities (using Kaufman Assessment Battery for Children [K-ABC] and the cognitive domain of Bayley Scales of Infant Development-II [BSID-II]) were assessed at baseline and at 8 weeks after treatment.
Results
There was no baseline difference between the two groups. In the THR group, there were statistically significant improvements in most domains after THR including receptive and expressive language and cognition compared to those before THR. In the control group, however, only receptive vocabulary ability assessed by REVT and cognitive function assessed by BSID-II showed improvements after conventional therapy. However, there were no statistically significant differences in language or cognitive abilities between the two groups at 8 weeks after treatment.
Conclusion
These results suggest that THR might improve language and cognitive abilities. Although the mechanisms and pathways involved in such improvements are currently unclear based on our findings, THR might have potential to optimize language and cognitive abilities of children with ASD and ID.

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  • Effectiveness of animal-assisted activities and therapies for autism spectrum disorder: a systematic review and meta-analysis
    Ningkun Xiao, Vaishnavi Bagayi, Dandan Yang, Xinlin Huang, Lei Zhong, Sergey Kiselev, Mikhail A. Bolkov, Irina A. Tuzankina, Valery A. Chereshnev
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    Ann-Marie Sylvia, Sofiya Alhassan, Katie Potter
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    Anastasia Kyvelidou, Edye Godden, Kaiti Otte, Katherine Smith, Kirk Peck, Martyna Adamiec, Emma Travis, Maya Almazloum, Dimitrios Katsavelis
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    Éva Suba-Bokodi, István Nagy, Marcell Molnár
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    Aynaz Shiri, Parviz Asgari, Reza Johari Fard, Fariba Hafezi
    Nursing and Midwifery Journal.2024; 22(9): 799.     CrossRef
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    Leanne O. Nieforth, A. J. Schwichtenberg, Marguerite E. O’Haire
    Review Journal of Autism and Developmental Disorders.2023; 10(2): 255.     CrossRef
  • Effects of Equine-Assisted Activities and Therapies for Individuals with Autism Spectrum Disorder: Systematic Review and Meta-Analysis
    Ningkun Xiao, Khyber Shinwari, Sergey Kiselev, Xinlin Huang, Baoheng Li, Jingjing Qi
    International Journal of Environmental Research and Public Health.2023; 20(3): 2630.     CrossRef
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    Giuseppa Maresca, Simona Portaro, Antonino Naro, Ramona Crisafulli, Antonio Raffa, Ileana Scarcella, Barbara Aliberti, Gaetano Gemelli, Rocco Salvatore Calabrò
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  • Effects of a Therapeutic Horseback Riding Program on Social Interaction and Communication in Children with Autism
    Mengxian Zhao, Shihui Chen, Yonghao You, Yongtai Wang, Yanjie Zhang
    International Journal of Environmental Research and Public Health.2021; 18(5): 2656.     CrossRef
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    Mirena Dimolareva, Thomas J. Dunn
    Journal of Autism and Developmental Disorders.2021; 51(7): 2436.     CrossRef
  • Recreational Horseback Riding and Its Association with Physical, Mental, and Social Wellbeing and Perceived Health
    Gabriele Schwarzmüller-Erber, Manfred Maier, Harald Stummer, Michael Kundi
    Anthrozoös.2021; 34(5): 685.     CrossRef
  • Otizm Spektrum Bozukluğu Olan Çocuklara Yönelik Hayvan Destekli Müdahalelerle Yürütülen Araştırmaların İncelenmesi
    Damla ÇETİN, Selmin ÇUHADAR
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    O. Petrusenko, I. Bodnar
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Fall Risk Assessment of Rural Elderly Population in Korea
Dahye Park, Hongsik Jo, Chul Ho Yoon, Eun Shin Lee, Min-Kyun Oh, Chang Han Lee
Ann Rehabil Med 2019;43(3):269-278.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.269
Objective
To investigate the risk factors for fall in the elderly population residing in rural areas of Korea and provide useful data for their prevention.
Methods
As part of farmers’ health promotion project, a retrospective study was conducted with a total of 350 elderly people recruited from March 2016 to December 2016. These subjects were divided into two groups: 254 non-fallers and 96 fallers. A person who fell to the floor at least once in the past year was defined as a faller. Participants were asked to visit the hospital once. The demographic characteristics, social environment, and educational levels were surveyed using a questionnaire. Physical examination was performed in the following order: cognitive function, lower leg strength and torque, body composition, and knee image test.
Results
Statistically significant factors for falls in univariate analysis were female gender, age, living alone, educational level less than middle school, skeletal muscle mass, Mini-Mental State Exam, knee osteoarthritis, hip torque, hip power mean, knee torque, and knee power mean. Multivariate analysis was performed to identify variables most relevant to falls among statistically significant factors in univariate logistic analysis. It was confirmed that female gender and age of 70–79 years were statistically significant factors related to falls.
Conclusion
Female gender and elderly status (70–79 years) are important risk factors for falls in rural areas underscoring the need for special attention when considering risk factors for falls among the elderly living in rural areas.

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  • Prevalence and Risk Factors for Fall among Rural Elderly: A County-Based Cross-Sectional Survey
    Hongping Zhang, Yinshaung Zhao, Feng Wei, Mo Han, Jianquan Chen, Songxu Peng, Yukai Du, Nan Jiang
    International Journal of Clinical Practice.2022; 2022: 1.     CrossRef
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    Jung Woo Lee, Seong Hun Kang, Hyo Geun Choi
    International Journal of Environmental Research and Public Health.2021; 18(7): 3758.     CrossRef
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    Guilherme Guarino de Moura Sá, Ana Maria Ribeiro dos Santos, Nelson Miguel Galindo Neto, Khelyane Mesquita de Carvalho, Carla Danielle Araújo Feitosa, Polyana Norberta Mendes
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  • Fall characteristics among elderly populations in urban and rural areas in Korea
    Myeongkyu Kim, Misoo Chang, Eunwoo Nam, Seul Gi Kim, Sung-il Cho, Dong Hee Ryu, Sin Kam, Bo Youl Choi, Mi Jung Kim
    Medicine.2020; 99(46): e23106.     CrossRef
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Effort Assessment of Stroke Patients in Physiotherapy Session by Accelerometry and Perceived Exertion Score: Preliminary Study
Justine Lacroix, Jean-Christophe Daviet, Jean-Yves Salle, Benoit Borel, Maxence Compagnat, Stephane Mandigout
Ann Rehabil Med 2019;43(3):262-268.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.262
Objective
To determine whether post-stroke patient’s perceived exertion correlates with effort intensity score as measured by a wearable sensor and to assess whether estimates of perceived exertion are correlated to the cerebral hemisphere involved in the stroke.
Methods
We evaluated the effort intensity score during physiotherapy sessions using a wearable sensor and subjects assessed their perceived exertion using the modified Borg CR10 Scale.
Results
Fifty-seven subacute stroke patients participated in the study. The correlation between perceived exertion rating and measured effort intensity was insignificant—mean (r=-0.04, p=0.78) and peak (r=-0.05, p=0.70). However, there was a significant difference (p<0.02) in the perceived exertion ratings depending on the cerebral hemisphere where the stroke occurred. Patients with left-hand side lesions rated their perceived exertion as 4.5 (min–max, 0.5–8), whereas patients with right-hand side lesions rated their perceived exertion as 5.0 (2–8).
Conclusion
While there was an insignificant correlation between perceived exertion and effort intensity measured by a wearable sensor, a consistent variations in perceived exertion estimates according to the side of the cerebral lesion was identified and established.

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    Emeline Gomes, Gemma Alder, Felicity A. S. Bright, Nada Signal
    Disability and Rehabilitation.2025; 47(3): 560.     CrossRef
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    Tracy Harington, Nicolette Comley-White, Ronel Roos
    South African Journal of Physiotherapy.2024;[Epub]     CrossRef
  • The Use of Samsung Health and ECG M-Trace Base II Applications for the Assessment of Exercise Tolerance in the Secondary Prevention in Patients after Ischemic Stroke
    Mateusz Lucki, Ewa Chlebuś, Agnieszka Wareńczak, Przemysław Lisiński
    International Journal of Environmental Research and Public Health.2021; 18(11): 5753.     CrossRef
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  • 126 Download
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Identifying Risk of Depressive Symptoms in Adults With Physical Disabilities Receiving Rehabilitation Services: Propensity Score Approaches
Yejin Lee, Ickpyo Hong, Mi Jung Lee, Hae Yean Park
Ann Rehabil Med 2019;43(3):250-261.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.250
Objective
To compare the risk of depressive symptoms in adults with physical disabilities between rehabilitationreceivers and non-receivers.
Methods
A total of 3,568 adults with physical disabilities were retrieved from the 2014 Korean National Survey on People with Disabilities database. Four covariate adjustment methods (a multivariable regression model, inverse probability of treatment weighting [IPTW] adjusted for normalized weight, IPTW with stabilized weight, and greedy algorithm with 1:1 propensity score matching) were used to estimate the odds of having depressive symptoms. The dependent variable was depressive symptoms and the independent variable was the use of rehabilitation services. Baseline covariates were 19 demographic variables and 10 chronic condition variables.
Results
The four covariate adjustment methods revealed that adults with physical disabilities receiving rehabilitation services had a higher risk of depressive symptoms than those who did not receive these services (adjusted odds ratio, 1.191–1.294).
Conclusion
Our findings suggest that adults with physical disabilities receiving rehabilitation services have higher risk of developing depressive symptoms. Therefore, rehabilitation professionals need to pay attention to depressive symptoms and establish therapeutic strategies that can reduce such risk in rehabilitation settings.

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    Christine T. Shiner, Ian Li, Michael Millard, Alison E.J. Mahoney
    Disability and Rehabilitation: Assistive Technology.2025; 20(3): 562.     CrossRef
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    Seongkum Heo, JungHee Kang, Tammy Barbé, JinShil Kim, Rhonda H. Slocumb, Brandy Haley, Nina Wright
    Journal of Cardiovascular Nursing.2025; 40(2): 133.     CrossRef
  • Factors associated with the use of rehabilitation services among people with disabilities in Chile: A population-based study
    Dania Silvia Paredes-Laguna, William Romeo Calderón-Curiñaupa, Sandra Liz Soto-Nuñez, Adriana Berenice Espinoza-Hoempler, J. Jhonnel Alarco
    F1000Research.2025; 12: 73.     CrossRef
  • Relationships of multidimensional factors to self-management in patients with diabetes: A Cross-sectional, correlational study
    Seongkum Heo, JungHee Kang, Tammy Barbé, JinShil Kim, Tara F. Bertulfo, Pattie Troyan, Daphnee Stewart, Erica Umeakunne
    Geriatric Nursing.2024; 55: 270.     CrossRef
  • Factors Associated With Self-management in Adults With Type 1 or Type 2 Diabetes
    Seongkum Heo, Tammy Barbé, JinShil Kim
    Journal of Cardiovascular Nursing.2024;[Epub]     CrossRef
  • Factors associated with the use of rehabilitation services among people with disabilities in Chile: A population-based study
    Dania Silvia Paredes-Laguna, William Romeo Calderón-Curiñaupa, Sandra Liz Soto-Nuñez, Adriana Berenice Espinoza-Hoempler, J. Jhonnel Alarco
    F1000Research.2023; 12: 73.     CrossRef
  • Effects of short birth interval on different forms of child mortality in Bangladesh: Application of propensity score matching technique with inverse probability of treatment weighting
    Mohammad Zahidul Islam, Md. Mostafizur Rahman, Md. Nuruzzaman Khan, Betregiorgis Hailu Zegeye
    PLOS ONE.2023; 18(4): e0284776.     CrossRef
  • The Role of Physical Activity and Depression on Quality of Life in Community-Dwelling Older Adults: Using Propensity Score Matching Approaches
    Suyeong Bae, Monique R. Pappadis, Sanghun Nam, Ickpyo Hong
    Journal of Aging and Physical Activity.2022; 30(5): 770.     CrossRef
  • Perceived Physical and Mental Health and Healthy Eating Habits During the COVID-19 Pandemic in Korea
    Yetsa A Tuakli-Wosornu, Uma Pandiyan, Catherine Stratton, Youngdeok Hwang, Abderrazak Hajjioui, Laura Paulina Muñoz-Velasco, Maryam Fourtassi, Rory Cooper, Joseph K Balikuddembe, Mark Peterson, Andrei Krassioukov, Angela Palomba, Deo Rishi Tripathi, Bo Yo
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
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    Desalegn Markos Shifti, Catherine Chojenta, Elizabeth Holliday, Deborah Loxton
    BMJ Open.2021; 11(8): e047892.     CrossRef
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  • 10 Crossref
Long-Term Effect of Rigid Foot Orthosis in Children Older Than Six Years With Flexible Flat Foot
Kyo-Jun Youn, So Young Ahn, Bong-Ok Kim, In Sik Park, Soo-Kyung Bok
Ann Rehabil Med 2019;43(2):224-229.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.224
Objective
To evaluate the long-term effect of a custom-made rigid foot orthosis (RFO) in children older than 6 years with pes planus (flat foot).
Methods
Medical records of 42 children diagnosed with flexible pes planus who were fitted with RFOs based on the inverted technique and underwent more than four consecutive radiological studies were reviewed. Resting calcaneal stance position (RCSP), anteroposterior talocalcaneal angle, lateral talocalcaneal angle, lateral talometatarsal angle, and calcaneal pitch were initially measured in both feet to evaluate alignment. Followup clinical and radiological evaluations were then performed at 12–18, 24–30, 36–42, and ≥48 months after RFO application. Repeated measures analysis of variance was used to evaluate significant differences.
Results
Significant improvements in all radiological indicators and significant progression of RCSP toward the corrective direction were observed after RFO application relative to baseline measurements.
Conclusion
According to our findings, RFO can induce significant improvements in calcaneus-related radiographic indices and subsequently improve talus-related radiologic indices.

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  • Effects of Rhythm Step Training on Foot and Lower Limb Balance in Children and Adolescents with Flat Feet: A Radiographic Analysis
    Ji-Myeong Park, Byung-Cho Min, Byeong-Chae Cho, Kyu-Ri Hwang, Myung-Ki Kim, Jeong-Ha Lee, Min-Jun Choi, Hyeon-Hee Kim, Myung-Sung Kang, Kyoung-Bin Min
    Medicina.2024; 60(9): 1420.     CrossRef
  • Change in Plantar Pressure and Plain Radiography in Pediatric Flexible Flatfoot: A Retrospective Cohort Study
    Sungjoon Kim, Yong Gyun Kim, Jun Yup Kim, Si-Bog Park, Kyu Hoon Lee
    Annals of Rehabilitation Medicine.2024; 48(5): 352.     CrossRef
  • Efficacy of Plantar Orthoses in Paediatric Flexible Flatfoot: A Five-Year Systematic Review
    Cristina Molina-García, George Banwell, Raquel Rodríguez-Blanque, Juan Carlos Sánchez-García, Andrés Reinoso-Cobo, Jonathan Cortés-Martín, Laura Ramos-Petersen
    Children.2023; 10(2): 371.     CrossRef
  • Radiologic changes of long term foot insole use in symptomatic pediatric flatfoot
    Joon Yeop Kim, Soo A Kim, Yuntae Kim, Insu Hwang, Nam Hun Heo
    Medicine.2023; 102(10): e33152.     CrossRef
  • "The Benefits of Physical Therapy in the Rehabilitation of Flat Feet in Autism Students between the ages of 10 and 14"
    Anca-Cristina POP, Ioan-Cosmin BOCA, Manuela-Ecaterina RUSU, Dana CRISTEA
    Romanian Journal of Physical Therapy.2023; 29(51): 32.     CrossRef
  • Monitoring the Role of Physical Activity in Children with Flat Feet by Assessing Subtalar Flexibility and Plantar Arch Index
    Ligia Rusu, Mihnea Ion Marin, Michi Mihail Geambesa, Mihai Robert Rusu
    Children.2022; 9(3): 427.     CrossRef
  • Relation of Flatfoot Severity with Flexibility and Isometric Strength of the Foot and Trunk Extensors in Children
    Min Hwan Kim, Sangha Cha, Jae Eun Choi, Minsoo Jeon, Ja Young Choi, Shin-Seung Yang
    Children.2022; 10(1): 19.     CrossRef
  • Relationships Between Relative Ankle Muscle Ratios, Severity of Symptoms, and Radiologic Parameters in Adolescent Patients With Symptomatic Flexible Flat Feet
    Youngju Shin, So Young Ahn, Soo-Kyung Bok
    Annals of Rehabilitation Medicine.2021; 45(2): 123.     CrossRef
  • Effect of Foot Orthoses in Children With Symptomatic Flexible Flatfoot Based on Ultrasonography of the Ankle Invertor and Evertor Muscles
    Dong Joon Cho, So Young Ahn, Soo-Kyung Bok
    Annals of Rehabilitation Medicine.2021; 45(6): 459.     CrossRef
  • Flat Foot and Postural Harmony in 6-Year-Old Caucasians: What is Their Relationship?
    Teresa Paolucci, Letizia Pezzi, Alice Mannocci, Giuseppe La Torre, Rosa Grazia Bellomo, Raoul Saggini
    Annals of Rehabilitation Medicine.2020; 44(4): 320.     CrossRef
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    A. Danyschuk
    Health, sport, rehabilitation.2019; 5(2): 28.     CrossRef
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  • 9 Web of Science
  • 11 Crossref
Effects of Copy Number Variations on Developmental Aspects of Children With Delayed Development
Kee-Boem Park, Kyung Eun Nam, Ah-Ra Cho, Woori Jang, Myungshin Kim, Joo Hyun Park
Ann Rehabil Med 2019;43(2):215-223.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.215
Objective
To determine effects of copy number variations (CNV) on developmental aspects of children suspected of having delayed development.
Methods
A retrospective chart review was done for 65 children who underwent array-comparative genomic hybridization after visiting physical medicine & rehabilitation department of outpatient clinic with delayed development as chief complaints. Children were evaluated with Denver Developmental Screening Test II (DDST-II), Sequenced Language Scale for Infants (SELSI), or Preschool Receptive-Expressive Language Scale (PRES). A Mann-Whitney U test was conducted to determine statistical differences of developmental quotient (DQ), receptive language quotient (RLQ), and expressive language quotient (ELQ) between children with CNV (CNV(+) group, n=16) and children without CNV (CNV(–) group, n=37).
Results
Of these subjects, the average age was 35.1 months (mean age, 35.1±24.2 months). Sixteen (30.2%) patients had copy number variations. In the CNV(+) group, 14 children underwent DDST-II. In the CNV(–) group, 29 children underwent DDSTII. Among variables, gross motor scale was significantly (p=0.038) lower in the CNV(+) group compared with the CNV(–) group. In the CNV(+) group, 5 children underwent either SELSI or PRES. In the CNV(–) group, 27 children underwent above language assessment examination. Both RLQ and ELQ were similar between the two groups.
Conclusion
The gross motor domain in DQ was significantly lower in children with CNV compared to that in children without CNV. This result suggests that additional genetic factors contribute to this variability. Active detection of genomic imbalance could play a vital role when prominent gross motor delay is presented in children with delayed development.

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  • Novel JAG1 variants leading to Alagille syndrome in two Chinese cases
    Xiufang Feng, Jiangyuan Ping, Shan Gao, Dong Han, Wenxia Song, Xiaoze Li, Yilun Tao, Lihong Wang
    Scientific Reports.2024;[Epub]     CrossRef
  • Copy Number Variation and Structural Genomic Findings in 116 Cases of Sudden Unexplained Death between 1 and 28 Months of Age
    Catherine A. Brownstein, Elise Douard, Robin L. Haynes, Hyun Yong Koh, Alireza Haghighi, Christine Keywan, Bree Martin, Sanda Alexandrescu, Elisabeth A. Haas, Sara O. Vargas, Monica H. Wojcik, Sébastien Jacquemont, Annapurna H. Poduri, Richard D. Goldstei
    Advanced Genetics.2023;[Epub]     CrossRef
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    Xingya Song, Xinmiao Li, Xian Liu, Zijing Zhang, Xiaoting Ding, Yanan Chai, Zhiming Li, Hongli Wang, Jungang Li, Huifeng Liang, Xiaoyan Sun, Guojie Yang, Zengfang Qi, Fuying Chen, Qiaoting Shi, Eryao Wang, Baorui Ru, Chuzhao Lei, Hong Chen, Wujun Liu, Yon
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    Nadja Louw, Nadia Carstens, Zané Lombard
    Frontiers in Genetics.2023;[Epub]     CrossRef
  • CNV profiles of Chinese pediatric patients with developmental disorders
    Haiming Yuan, Shaofang Shangguan, Zhengchang Li, Jingsi Luo, Jiasun Su, Ruen Yao, Shun Zhang, Chen Liang, Qian Chen, Zhijie Gao, Yanli Zhu, Shujie Zhang, Wei Li, Weiliang Lu, Yu Zhang, Hua Xie, Fang Liu, Qingming Wang, Yangyang Lin, Liying Liu, Xiuming Wa
    Genetics in Medicine.2021; 23(4): 669.     CrossRef
  • Copy Number Variation: Methods and Clinical Applications
    Ondrej Pös, Jan Radvanszky, Jakub Styk, Zuzana Pös, Gergely Buglyó, Michal Kajsik, Jaroslav Budis, Bálint Nagy, Tomas Szemes
    Applied Sciences.2021; 11(2): 819.     CrossRef
  • 7,983 View
  • 114 Download
  • 5 Web of Science
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Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Polydeoxyribonucleotide in the Treatment of Knee Osteoarthritis
Seihee Yoon, Jung Joong Kang, Jungin Kim, Seunghun Park, Jong Moon Kim
Ann Rehabil Med 2019;43(2):204-214.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.204
Objective
To assess the clinical efficacy and safety of intra-articular injection of hyaluronic acid (HA) combined with polydeoxyribonucleotide (PDRN) in patients with knee osteoarthritis in comparison with that of HA alone.
Methods
The current single-center, prospective, randomized, double-blind, controlled study was conducted in 36 patients with knee osteoarthritis at our medical institution. All the eligible patients (n=30) were equally assigned to two treatment arms (trial group ‘HA+PDRN’ and control group ‘HA’). For efficacy assessment, the patients were evaluated for the visual analogue scale (VAS) scores, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Knee Society Scores (KSS), all of which served as efficacy outcome measures. We monitored time-dependent changes in efficacy outcome measures at baseline and 1, 3 and 6 months. Subsequently, we compared differences in changes in efficacy outcome measures at 6 months from baseline between the two groups. Moreover, we assessed the safety based on the treatment-emergent adverse events (TEAEs), adverse drug reactions (ADRs) and any other complications serving as safety outcome measures.
Results
There were significant differences in changes in the VAS scores, the WOMAC scores in all domains, except ‘Stiffness’, the total WOMAC scores, and the KSS scores in all the domains at 6 months from baseline between the two groups (p<0.05). In our series, there were no TEAEs, ADRs, and any other complications.
Conclusion
Intra-articular injections of HA combined with PDRN can also be considered in the treatment of knee osteoarthritis. However, further large-scale and multi-center studies are required to demonstrate the potential of the proposed combination.

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  • 14 Web of Science
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Correlation of the Korean Version of Falls Efficacy Scale-International With Quantitative Balance and Gait Parameters Through Exercise Program in Elderly Men
Bo Ram Ahn, Hyo Jung Kang, Eun Jung Choi, Soo Woong Jang, Hee Sup Chung, Kyung Soo Jeon
Ann Rehabil Med 2019;43(2):195-203.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.195
Objective
To determine correlation of the Korean version of Falls Efficacy Scale-International (KFES-I) with other gait and balance parameters through exercise program in older men.
Methods
Between July 2015 and April 2018, 50 men of 103 participants in an exercise program for preventing falls who aged over 60 years, completed the evaluation before and after the program, had fear of falling (FOF), and could walk independently as an outpatient were enrolled retrospectively. The program comprised lower extremities and core muscle strengthening exercises following stretching exercises twice a week for 8 weeks. FOF using the KFES-I, Berg Balance Scale (BBS), Modified Barthel Index (MBI), stair up and gait categories in MBI (MBI-gait), and Timed Up and Go test (TUG) were evaluated. Quantitative gait and balance parameters were measured by gait analysis, posturography, and isokinetic dynamometer. They were compared before and after the program. Moreover, correlations of KFES-I with other parameters were examined.
Results
Fifty participants were enrolled. After the program, significant improvements were noted in right stride length (p=0.013) in gait analysis, MBI (p=0.012), BBS (p<0.000), TUG test (p<0.000), and KFES-I (p<0.000) scores. KFES-I was significantly correlated with MBI (r=-0.35, p=0.013), and MBI-gait (r=-0.341, p=0.015).
Conclusion
Risk of falls could be significantly improved through exercise. KFES-I had significant correlations with MBI-gait parameters. Participants showed increases in gait and balancing ability on quantitative measurements through exercises. Therefore, regular stretching, strengthening, and balancing exercises may help prevent falls in older people.

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    Kap-Soo Han, Myoung-Hwan Ko
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    Eun-Lee Lee, Myoung-Hwan Ko, Myung-Jun Shin, Byeong-Ju Lee, Da Hwi Jung, Kap-Soo Han, Jin Mi Kim
    Journal of the American Medical Directors Association.2022; 23(3): 373.     CrossRef
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    Chun-Tung Kuo, Duan-Rung Chen, Ya-Mei Chen, Peng-Yu Chen
    Geriatric Nursing.2021; 42(5): 1012.     CrossRef
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    Fanny Buckinx, Olivier Bruyère, Laetitia Lengelé, Jean-Yves Reginster, Quentin Marchal, Paulin Hurtrez, Alexandre Mouton
    Experimental Gerontology.2020; 138: 110983.     CrossRef
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  • 139 Download
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Predictive Value of Pharyngeal Width at Rest (JOSCYL Width) for Aspiration in Elderly People
Ho Young Lee, Il Hwan Jung, Eunsil Cha, Jimin Song, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
Ann Rehabil Med 2019;43(2):187-194.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.187
Objective
To develop a new tool for aspiration risk prediction based on pharyngeal width at rest in older adults with symptoms of aspiration.
Methods
Lateral cervical spine roentgenograms were obtained from 33 older adult patients who complained of dysphagia and from 33 healthy, age-matched controls. Pharyngeal width at rest was measured at two points. We named the average of these two pharyngeal widths ‘JOSCYL Width’, calculated ‘JOSCYL Scale’, and compared these parameters between dysphagia and control groups. Correlations of individual JOSCYL Width and JOSCYL Scale, with Penetration Aspiration Scale (PAS) and Dysphagia Outcome and Severity Scale (DOSS) scores were analyzed for the dysphagia group. To determine optimal cutoff points for predicting aspiration, a receiver operating characteristic curve analysis was performed on JOSCYL Width and JOSCYL Scale.
Results
Both JOSCYL Width and JOSCYL Scale of the dysphagia group were larger than those of the control group (p<0.001). The correlation between JOSCYL Width and severity of dysphagia was significant for the dysphagia group (PAS p=0.007; DOSS p=0.012). The correlation between JOSCYL Scale and the severity of dysphagia was also significant for the dysphagia group (PAS p=0.009; DOSS p=0.011). Optimal cutoffs for JOSCYL Width and JOSCYL Scale for predicting aspiration were 20.0 mm and 5.9, respectively.
Conclusion
JOSCYL Width and JOSCYL Scale can be new indicators for predicting aspiration in older adults. They are both precise and easy to use.

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    Eunjee Lee, Gyu Jin Kim, Hyewon Ryu, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    Dysphagia.2024; 39(3): 468.     CrossRef
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    Howell Henrian G. Bayona, Yoko Inamoto, Eichii Saitoh, Keiko Aihara, Masanao Kobayashi, Yohei Otaka
    Dysphagia.2024; 39(5): 783.     CrossRef
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    Wonil Kang, Jane Chung, Jeongeun Lee, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    NeuroRehabilitation.2021; 49(3): 435.     CrossRef
  • Changes in Pharyngeal Width Over Time as an Indicator of Dysphagia in Stroke Patients
    Seungki Baek, Il Hwan Jung, Ho Young Lee, Jimin Song, Eunsil Cha, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
    Annals of Rehabilitation Medicine.2020; 44(3): 203.     CrossRef
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Scapular Upward Rotation During Passive Humeral Abduction in Individuals With Hemiplegia Post-stroke
Jonjin Ratanapinunchai, Witaya Mathiyakom, Somporn Sungkarat
Ann Rehabil Med 2019;43(2):178-186.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.178
Objective
To describe scapular upward rotation during passive humeral abduction in individuals with hemiplegia post-stroke compared to normal subjects.
Methods
Twenty-five individuals with hemiplegia post-stroke and 25 age- and gender-matched normal subjects voluntarily participated in this study. Scapular upward rotation during resting and passive humeral abduction at 30°, 60°, 90°, 120°, and 150° were measured using a digital inclinometer.
Results
In both groups, scapular upward rotation significantly increased as humeral abduction increased (p<0.001). Scapular upward rotation was significantly less in the hemiplegic group compared to that in the control at 90° (p=0.002), 120° (p<0.001), and 150° of humeral abduction (p<0.001). The mean difference in scapular upward rotation between these two groups ranged from 6.3° to 11.38°.
Conclusion
Passive humeral abductions ranging from 90° to 150° can significantly alter scapular upward rotation in individuals with hemiplegia post-stroke compared to those of matched normal subjects. The magnitude of reduction of the scapular upward rotation may potentially lead to the development of hemiplegic shoulder pain after prolonged repetitive passive movement. Scapular upward rotation should be incorporated during passive humeral abduction in individuals with hemiplegia post-stroke, especially when the humeral is moved beyond 90° of humeral abduction. Combined movements of scapular and humeral will help maintain the relative movement between the scapula and humerus. However, further longitudinal study in patients with shoulder pain post-stroke is needed to confirm these findings.

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    Binoy B. Nair, N. R. Sakthivel
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Duration of Treatment Effect of Extracorporeal Shock Wave on Spasticity and Subgroup-Analysis According to Number of Shocks and Application Site: A Meta-Analysis
Jae Ho Oh, Hee Dong Park, Seung Hee Han, Ga Yang Shim, Kyung Yeul Choi
Ann Rehabil Med 2019;43(2):163-177.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.163
Objective
To investigate duration of the treatment effect of extracorporeal shockwave therapy (ESWT) on spasticity levels measured with Modified Ashworth Scale (MAS) regardless of the patient group (stroke, multiple sclerosis, and cerebral palsy) and evaluate its spasticity-reducing effect depending on the number of shocks and site of application.
Methods
PubMed, EMBASE, the Cochrane Library, and Scopus were searched from database inception to February 2018. Randomized controlled trials and cross-over trials were included. All participants had spasticity regardless of cause. ESWT was the main intervention and MAS score was the primary outcome. Among 122 screened articles, 9 trials met the inclusion criteria.
Results
The estimate of effect size showed statistically significant MAS grade reduction immediately after treatment (standardized mean difference [SMD]=-0.57; 95% confidence interval [CI], -1.00 to -0.13; p=0.012), 1 week after (SMD=-1.81; 95% CI, -3.07 to -0.55; p=0.005), 4 weeks after (SMD=-2.35; 95% CI, -3.66 to -1.05; p<0.001), and 12 weeks after (SMD=-1.07; 95% CI, -2.04 to -0.10; p=0.03). Meta-regression and subgroup analysis were performed for the ‘immediately after ESWT application’ group. The prediction equation obtained from metaregression was -1.0824+0.0002* (number of shocks), which was not statistically significant. Difference in MAS grade reduction depending on site of application was not statistically significant either in subgroup analysis (knee and ankle joints vs. elbow, wrist, and finger joints).
Conclusion
ESWT effectively reduced spasticity levels measured with MAS regardless of patient group. Its effect maintained for 12 weeks. The number of shocks or site of application had no significant influence on the therapeutic effect of ESWT in reducing spasticity. Ongoing trials with ESWT are needed to address optimal parameters of shock wave to reduce spasticity regarding intensity, frequency, and numbers.

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    Boris S.G. Hellenbrand, Charlotte C.M. van Laake – Geelen, Henk A.M. Seelen
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  • Using Radial Shock Wave Therapy to Control Cerebral Palsy-Related Dysfunctions: A Randomized Controlled Trial
    Hisham Hussein, Ahmed Gabr, Monira Aldhahi, Amsha Alshammari, Hand Alshammari, Khulood Altamimi, Abdulaziz Alqahtani, Ibrahim Dewir, Shamekh El-Shamy, Ahmed Ibrahim
    International Journal of General Medicine.2025; Volume 18: 1439.     CrossRef
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    Takatsugu Okamoto, Takumi Watanabe, Shogo Uemori
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    Sheng Li, Paul Winston, Manuel F. Mas
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    Binash Afzal, Rabiya Noor, Nazia Mumtaz, Muhammad Salman Bashir
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    Tingyu Zhang, Cai Zhang
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Correlation of Swallowing Function With Bilateral Diaphragmatic Movement in Hemiplegic Stroke Patients
Ra Yu Yun, Ho Eun Park, Ji Won Hong, Yong Beom Shin, Jin A Yoon
Ann Rehabil Med 2019;43(2):156-162.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.156
Objective
To investigate difference in bilateral diaphragm movement of patients with tracheal aspiration according to post stroke residue severity and determine correlations of Penetration-Aspiration Scale (PAS), residue scale, and bilateral diaphragm movement.
Methods
A total of 47 patients diagnosed with hemiplegic stroke were enrolled in this study. PAS, severity of valleculae, and pyriform sinus retention during videofluoroscopic swallowing study (VFSS) were assessed. Bilateral fluoroscopic diaphragm movements during spontaneous breathing and forced breathing were measured.
Results
Patients with tracheal aspiration (PAS≥6) had significantly (p=0.035) lower ipsilateral diaphragm movement during spontaneous breathing. Post-swallow residue severity showed statistically significant (p=0.028) difference in patients with ipsilateral diaphragm movement during forced breathing. In linear regression analysis, PAS showed weak correlations with ipsilateral spontaneous diaphragm movement (r=0.397, p=0.006), ipsilateral forced diaphragm movement (r=0.384, p=0.008), and contralateral forced diaphragm movement (r=0.323, p=0.027). Weak correlation was also observed between post swallow residue severity and ipsilateral diaphragm movement during spontaneous breathing (r=0.331, p=0.023) and forced breathing (r=0.343, p=0.018).
Conclusion
We confirmed the relationship between swallowing function and bilateral diaphragm movement in this study. The severity of dysphagia after hemiplegic stroke was correlated with bilateral diaphragm movement. Further longitudinal studies are needed to assess the effect of breathing exercise on post-stroke dysphagia.

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    Toru Yamada, Taro Minami, Takahiro Shinohara, Shuji Ouchi, Suguru Mabuchi, Shunpei Yoshino, Ken Emoto, Kazuharu Nakagawa, Kanako Yoshimi, Mitsuko Saito, Ayane Horike, Kenji Toyoshima, Yoshiaki Tamura, Atsushi Araki, Ryoichi Hanazawa, Akihiro Hirakawa, Tak
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Comparison of Dysphagia Between Infratentorial and Supratentorial Stroke Patients
Yong Kyun Kim, Jung Hyun Cha, Kyun Yeon Lee
Ann Rehabil Med 2019;43(2):149-155.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.149
Objective
To compare dysphagia between infratentorial stroke patients and supratentorial stroke patients.
Methods
Subjects of this study were patients with post-stroke dysphagia (PSD) who were admitted to our medical institution between May 2014 and June 2017. We evaluated a total of 64 patients with PSD. A videofluoroscopic swallowing study (VFSS) was performed to determine dysphagia severity. We measured the following parameters: pharyngeal transit time (PTT), post-swallow pharyngeal remnant, Penetration Aspiration Scale (PAS) scores, and Functional Dysphagia Scale (FDS). We analyzed patient’s results from VFSS performed at admission. All VFSS images were recorded using a camcorder running at 30 frames per second. An AutoCAD 2D screen was used to measure post-swallow pharyngeal remnant.
Results
In this study, PTT and FDS were similar (p>0.05) between infratentorial stroke patients and supratentorial stroke patients. However, there were significant differences in pharyngeal remnant and PAS scores between the two groups (p<0.01 and p<0.05, respectively).
Conclusion
Both pharyngeal remnant and PAS score registered higher levels from VFSS test for infratentorial stroke patients than those for supratentorial stroke patients. This suggests greater chances of problems occurring with swallowing, the major functions of pons. Thus, clinicians should pay particular attention to active dysphagia evaluation and treatment in PSD of infratentorial stroke patients.

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  • Investigation of neurogenic dysphagia in commonly seen neurological diseases
    Müberra Tanrıverdi, Senanur Düzenli, Merve Sevinç Gündüz, Ayça Arslantürk, Ayşenur Erekdağ
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    Zicong Wang, Ran Shi, Paulo Moreira
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    Journal of Stroke and Cerebrovascular Diseases.2024; 33(6): 107682.     CrossRef
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    Qingxian Fan, Yan Zhao, Jianrong Zhang, Yu’e Wu, Qingping Huang, Ying Gao, Jingqin Wang, Changqiong Guo, Shuqing Zhang
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    Meng Dai, Jia Qiao, Zhonghui Shi, Xiaomei Wei, Huayu Chen, Luxi Shen, Hongmei Wen, Zulin Dou
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    Jong Keun Kim, Sangpil Son, InHyuk Suh, Jin Seok Bae, Jong Youb Lim
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    Daham Kim, Jae-Hyung Kim, Si-Woon Park, Hyung-Wook Han, Sang Joon An, Yeong In Kim, Hyo Jin Ju, YoonHee Choi, Doo Young Kim
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  • The influence of pharyngeal width on post-stroke laryngeal aspiration
    Wonil Kang, Jane Chung, Jeongeun Lee, Kwang-Ik Jung, Woo-Kyoung Yoo, Suk Hoon Ohn
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Association Between Duration of Dysphagia Recovery and Lesion Location on Magnetic Resonance Imaging in Patients With Middle Cerebral Artery Infarction
Jae Ho Kim, Se Hyun Oh, Ho Joong Jeong, Young Joo Sim, Dung Gyu Kim, Ghi Chan Kim
Ann Rehabil Med 2019;43(2):142-148.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.142
Objective
To investigate association between lesion location on magnetic resonance imaging (MRI) performed after an infarction and the duration of dysphagia in middle cerebral artery (MCA) infarction.
Methods
A videofluoroscopic swallowing study was performed for 59 patients with dysphagia who were diagnosed as cerebral infarction of the MCA territory confirmed by brain MRI. Lesions were divided into 11 regions of interest: primary somatosensory cortex, primary motor cortex, supplementary motor cortex, anterior cingulate cortex, orbitofrontal cortex, parieto-occipital cortex, insular cortex, posterior limb of the internal capsule (PLIC), thalamus, basal ganglia (caudate nucleus), and basal ganglia (putamen). Recovery time was defined as the period from the first day of L-tube feeding to the day that rice porridge with thickening agent was prescribed. Recovery time and brain lesion patterns were compared and analyzed.
Results
The mean recovery time of all patients was 26.71±16.39 days. The mean recovery time was 36.65±15.83 days in patients with PLIC lesions and 32.6±17.27 days in patients with caudate nucleus lesions. Only these two groups showed longer recovery time than the average recovery time for all patients. One-way analysis of variance for recovery time showed significant differences between patients with and without lesions in PLIC and caudate (p<0.001).
Conclusion
Injury to both PLIC and caudate nucleus is associated with longer recovery time from dysphagia.

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