Holmes' tremor is a low-frequency rest and intentional tremor secondary to various insults, including cerebral ischemia, hemorrhage, trauma, or neoplasm. Pharmacologic treatment is usually unsuccessful, and some cases require surgical intervention. We report a rare case of Holmes' tremor secondary to left pontine hemorrhage in a 29-year-old Asian male patient who developed 1.6-Hz postural and rest tremor of the right hand. He responded markedly to ultrasonography-guided botulinum toxin type A injection. To our knowledge, this is the first report of Homes' tremor treated with ultrasonography-guided botulinum toxin type A injection with favorable results.

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• Ultrasonography for Assessment and Intervention With Botulinum Toxin Injection for Tremors
  So-Hyun Park, Joon-Ho Shin
  Annals of Rehabilitation Medicine.2024; 48(6): 396.     CrossRef
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  Pamela Latino, Francesco E. Pontieri, Francesco Orzi, Morena Giovannelli
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