To evaluate the short-term effectiveness of pulsed radiofrequency on the dorsal root ganglion (DRG) in patients with chronic refractory cervical radicular pain.
Method
Fifteen patients (13 males, 2 females; mean age, 55.9 years) with chronic radicular pain due to cervical disc herniation or foraminal stenosis refractory to active rehabilitative management, including transforaminal cervical epidural steroid injection and exercise, were selected. All patients received pulsed radiofrequency on the symptomatic cervical dorsal root ganglion and were carefully evaluated for neurologic deficits and side effects. The clinical outcomes were measured using a visual analogue scale (VAS) and a neck disability index (NDI) before treatment, one and three months after treatment. Successful pain relief was defined as a 50% or greater reduction in the VAS score as compared with the pre-treatment score. After three months, we categorized the patients' satisfaction.
Results
The average VAS for radicular pain was reduced significantly from 5.3 at pretreatment to 2.5 at 3 months post-treatment (p<0.05). Eleven of 15 patients (77.3%) after cervical pulsed RF stimulation reported pain relief of 50% or more at the 3 month follow-up. The average NDI was significantly reduced from 44.0% at pretreatment to 35.8% 3 months post-treatment (p<0.05). At 3 months post-treatment, eleven of fifteen patients (73.3%) were satisfied with their status. No adverse effects were observed.
Conclusion
The results demonstrate that the application of pulsed radiofrequency on DRG might be an effective short-term intervention for chronic refractory cervical radicular pain. Further studies, including a randomized controlled trial with long-term follow-up, are now needed.
Citations
Citations to this article as recorded by
Pulsed Radiofrequency Stimulation for Radicular Pain Dong Gyu Lee Clinical Pain.2024; 23(2): 79. CrossRef
Comparison between ultrasound-guided monopolar and bipolar pulsed radiofrequency treatment for refractory chronic cervical radicular pain: A randomized trial Sang Hoon Lee, Hyun Hee Choi, Min Cheol Chang Journal of Back and Musculoskeletal Rehabilitation.2022; 35(3): 583. CrossRef
Safety of Conventional and Pulsed Radiofrequency Lesions of the Dorsal Root Entry Zone Complex (DREZC) for Interventional Pain Management: A Systematic Review Mila Pastrak, Ognjen Visnjevac, Tanja Visnjevac, Frederick Ma, Alaa Abd-Elsayed Pain and Therapy.2022; 11(2): 411. CrossRef
A Literature Review of Dorsal Root Entry Zone Complex (DREZC) Lesions: Integration of Translational Data for an Evolution to More Accurate Nomenclature Ognjen Visnjevac, Frederick Ma, Alaa Abd-Elsayed Journal of Pain Research.2021; Volume 14: 1. CrossRef
Efficacy and Safety of Pulsed Radiofrequency as a Method of Dorsal Root Ganglia Stimulation in Patients with Neuropathic Pain: A Systematic Review Ivana Vuka, Tihana Marciuš, Svjetlana Došenović, Lejla Ferhatović Hamzić, Katarina Vučić, Damir Sapunar, Livia Puljak Pain Medicine.2020; 21(12): 3320. CrossRef
Effectiveness of pulsed radiofrequency treatment on cervical radicular pain Sang Gyu Kwak, Dong Gyu Lee, Min Cheol Chang Medicine.2018; 97(31): e11761. CrossRef
A comprehensive review of pulsed radiofrequency in the treatment of pain associated with different spinal conditions Giancarlo Facchini, Paolo Spinnato, Giuseppe Guglielmi, Ugo Albisinni, Alberto Bazzocchi The British Journal of Radiology.2017; 90(1073): 20150406. CrossRef
The Effect of Pulsed Radiofrequency Applied to the Peripheral Nerve in Chronic Constriction Injury Rat Model Jun-Beom Lee, Jeong-Hyun Byun, In-Sung Choi, Young Kim, Ji Shin Lee Annals of Rehabilitation Medicine.2015; 39(5): 667. CrossRef
Cervical disc herniation: Is the regression flawed by age? A case report Emanuele Di Ciaccio, Massimiliano Polastri, Alessandro Gasbarrini International Journal of Therapy and Rehabilitation.2013; 20(12): 612. CrossRef