Fahr’s disease (FD) is a rare neurologic disorder characterized by the symmetric and bilateral intracerebral calcification in a patient. We describe the case of a 65-year-old woman who presented with gait disturbance, abnormal mentality, and visual field defect. The result of a brain computerized tomography showed spontaneous intracranial hemorrhage in the right parieto-occipital area, and also showed the incidence of symmetric and bilateral intracerebral calcification. Moreover, laboratory studies indicated characteristic hypoparathyroidism. This brings us to understand that additionally, one of her sons also presented with similar intracerebral calcification, and was subsequently diagnosed with FD. Thus, her case was consistent with that of a patient experiencing FD. The patient had hypertension, which we now know might have caused the intracerebral hemorrhage. However, this patient’s brain lesions were in uncommon locations for spontaneous intracerebral hemorrhage, and the lesions were noted as occurring away from the identified heavily calcified areas. Thus, it seemed that the massive calcification of cerebral vessels in the basal ganglia, the most common site of intracerebral hemorrhage, might have prevented a hypertensive intracerebral hemorrhage. Eventually, an intracerebral hemorrhage occurred in an uncommon location in the patient’s brain.
Citations
Citations to this article as recorded by
Aneurysmal subarachnoid hemorrhage with PFBC and beta thalassemia: a case report Kuangyang Yu, Jinwei Pang, Xiaobo Yang, Jianhua Peng, Yong Jiang BMC Neurology.2023;[Epub] CrossRef
Decoding brain calcifications: A single-center descriptive case series and examination of pathophysiological mechanisms Bahadar S Srichawla, Eduardo Andrade, Vincent Kipkorir SAGE Open Medical Case Reports.2023;[Epub] CrossRef
Fahr’s syndrome associated with hypoparathyroidism: A case report Mukesh Kumar Sarna, Pallaavi Goel, Varun Bhargava, Rishabh Parakh Journal of the Royal College of Physicians of Edinburgh.2023; 53(4): 283. CrossRef
Nontraumatic spontaneous bilateral intracerebral haemorrhage in a young patient: a rare case report Pramodman Singh Yadav, Sagar Panthi, Aakash Neupane, Manish Uprety, Rochana Acharya, Leeza Shah, Ajmat Ansari, Ujjwal Basnet, Raksha Bhattarai, Bhawani Khanal Annals of Medicine & Surgery.2023; 85(5): 1830. CrossRef
Hypoparathyroidism with Fahr’s syndrome: A case report and review of the literature Yuan-Yuan Zhou, Ying Yang, Hong-Mei Qiu World Journal of Clinical Cases.2019; 7(21): 3662. CrossRef